Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 121 for “"Zika"”.
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Zika Message Analysis
<p>The following study employs the Extended Parallel Processing Model and Theory of Planned Behavior to understand how to create health messages with the greatest influence on individuals’ behavioral intent to adopt mosquito-borne virus protection behaviors. The study employs a 2 (susceptibility) x …
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An Examination of the Safety and Efficacy of Aripo-Zika as a Zika Virus Vaccine Candidate
… such as Dengue, West Nile, yellow fever and Zika viruses are globally distributed. Zika virus (ZIKV) is a single strand positive-sense RNA virus, and its disease has been linked to Guillain Barré Syndrome (i.e., a debilitating autoimmune disorder that affects the nerves) in adults and …
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Neuro-zika: Brain structure and functional organization of adult humans with zika virus infection and severe neurological complications
Since its outbreak in the Americas in 2015, Zika virus (ZIKV) has become a major global health threat due to its potential to affect the nervous system. Although most adult cases show no or mild symptoms, some patients exhibit severe neurological complications. While these complications often …
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Zika Modulates Arthropod Histone Methylation in Mosquito Cells
… or proteins. Recent studies have reported that Zika virus (ZIKV) modulates methylation of human and viral RNA important for its replication in vertebrate cells. However, little is known whether ZIKV exerts methylation in arthropod vectors. In this study, I show that ZIKV modulates S-adenosyl …
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Innate immunity in Zika Virus infection and neurogenesis deficits
Zika virus (ZIKV) outbreaks and their strong link to microcephaly have raised public health concerns globally. Clinical and animal studies have shown that miscarriage and brain malformation are more frequent when infection occurs during early pregnancy. ZIKV-associated microcephaly is most likely …
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Mechanistic analysis of the Zika virus translation-replication switch
… during infection must be tightly regulated. Zika virus (ZIKV) is a capped, positive-sense RNA virus of the Flavivirus genus, which contains several notable human pathogens including Dengue virus (DENV) and Japanese encephalitis virus. Infection with ZIKV has been linked to congenital …
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Anormalidades eletroneuromiográficas em pacientes com síndrome congênita do Zika Vírus
A Síndrome Congênita do Zika é um padrão distinto de defeitos congênitos em fetos infectados pelo vírus Zika. Apresenta amplo espectro clínico, como microcefalia, hipertonia, disfagia, hiperexcitabilidade, convulsões e artrogripose. Nos exames de imagem podem ser visualizados distúrbios da migração …
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Functional analysis of glycosylation of Zika virus envelope and NS1 proteins
Zika virus (ZIKV) infection causes devastating congenital abnormities and Guillain-Barré syndrome. ZIKV has two important glycoproteins, both the envelope (E) protein, and nonstructural protein 1 (NS1). The ZIKV envelope (E) protein is responsible for viral entry and represents a major determinant …
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Functional analysis of glycosylation of Zika virus envelope and NS1 proteins
Zika virus (ZIKV) infection causes devastating congenital abnormities and Guillain-Barré syndrome. ZIKV has two important glycoproteins, both the envelope (E) protein, and nonstructural protein 1 (NS1). The ZIKV envelope (E) protein is responsible for viral entry and represents a major determinant …
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Bloodmeal determinants of Zika virus infection of Aedes (Stegomyia) aegypti mosquitoes
… (Stegomyia) spp. mosquitoes with the arboviruses Zika (ZIKV). It has been repeatedly observed in both flaviviruses and alphaviruses that bloodmeals taken from viremic animals are more infectious than artificial bloodmeals. Although this finding has been demonstrated to be at least in part mediated …
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Vector Competence of Aedes aegypti for Zika Virus and Effects of Colonization
… the vector competence of Aedes aegypti for Zika virus (ZIKV) as well as the microbiome as a correlating factor. Ae. aegypti is the vector of multiple arthropod-borne viruses including dengue, yellow fever, and Zika virus, making it one of the most globally significant disease vectors and is …
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Development of an Attenuated Zika Virus by Editing the 5’ Untranslated Region
<p>Zika Virus (ZIKV) is a mosquito-transmitted flavivirus that usually causes no symptoms to mild febrile in humans, and it has been regarded as an insignificant pathogen to public health. However, recent outbreaks of ZIKV infection have revealed that ZIKV can cause severe neurological effects in …
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Crescimento e neurodesenvolvimento de crianças com a Síndrome da Zika Congênita (Salvador - Bahia)
Background: After Zika virus (ZIKV) outbreak in Brazil and around the world in 2015, it started efforts to prevent, diagnosis new cases and treat children with Congenital Zika Syndrome (CZS) that was infected during intrauterine development. Methods: Based on a case-control study, it was evaluated …
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Ucwaningo olunzulu ngemvunulo yezinkondlo zika-D.B.Z. Ntuli, encwadini ka L.T.L. Mabuya: Ilaka lokulangazelela
Lolu cwaningo luhlose ukukhanyisa ukuthi ubunkondlo butholakala kanjani enkondlweni. Luzophawula ngezinyathelo ezithathwa umhluzi uma ehluza inkondlo. Lolu cwaningo luzobheka nokubumbeka kwengaphandle lalezi zinkondlo ezilandelayo : Inhlekelele YaseCoalbrook, Sithi Halala, Kuyona Ie ngabadi. …
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Acompanhamento audiológico de crianças com síndrome congênita associada à infecção pelo vírus zika
… congênita associada à infecção pelo vírus Zika (SCZ) é caracterizada por malformações congênitas encontradas em crianças infectadas pelo vírus Zika (ZIKV) durante a gestação e, embora seu espectro clínico ainda não esteja totalmente esclarecido, está associado a microcefalia, distúrbios …
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Investigating the importance of the Zika virus 3′ untranslated region to viral fitness
… Musashi 1 (MSI1) has been shown to bind to the Zika virus (ZIKV) 3′ untranslated region (3′UTR) and enhance viral replication. MSI1 is present in high levels in neural progenitor cells of the foetal brain, and previous work proposed that MSI1 could drive the pathogenesis caused by ZIKV, and …
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Validating Forecasting Strategies of Simple Epidemic Models on the 2015-2016 Zika Epidemic
… models. We use incidence data from the 2015-2016 Zika virus outbreak in Antioquia, Colombia, to assess what model features result in accurate forecasts. We employed the Parametric Bootstrapping and Ensemble Kalman Filter methods to assimilate data and then generated 14-day-ahead forecasts …
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Development, Characterization, and Use of Molecular Tools to Study Immune-Driven Zika Virus Evolution
… causes 400 million infections annually, and Zika virus (ZIKV), which caused over 128 million infections from 2013-2018. These viruses, which are cocirculating, share high sequence similarity in key antigenic regions. Because of these similarities, pre-existing immunity to DENV has been …
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Infecção por Zika Vírus: O que o profissional de saúde da atenção básica deve saber?
A história da infecção pelo Zika vírus no Brasil se iniciou ao fim de 2014, tendo ganhado crescente importância até 2016, a partir do reconhecimento da relação entre o Zika Vírus e a ocorrência de microcefalia e outros distúrbios neurológicos pelo Centers for Disease Control and Prevention (CDC). O …
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Impact of climate- and urbanization-driven environmental change on Aedes aegypti susceptibility to Zika virus
… adult traits, including susceptibility to Zika virus (ZIKV). Here, we tested the hypothesis that larval development with container-specific bacterial communities alters adult Ae. aegypti susceptibility to ZIKV. We found that plastic-derived microbiomes increase ZIKV susceptibility across …
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