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Showing 1 to 1 of 1 for “"Zebrafish, Intestine, Cancer, Transgenic, kras, Inducible"”.

  1. GENERATION AND ANALYSES OF krasV12 TRANSGENIC ZEBRAFISH TO STUDY INTESTINE TUMORIGENESIS

    Mutations in KRAS contribute to 40% of colorectal cancer cases. To explore the mechanism of krasV12 oncogene in intestine cancer we generated a novel inducible model in zebrafish. The stable transgenic zebrafish expressed krasV12 under a gut specific promoter and the EGFPkrasV12 enabled live …

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