Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"ZNF808"”.
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Primate-specific KRAB zinc finger proteins and their targets rewire regulatory networks related to inflammation and pancreas development
… aim to characterise the function of two KZFPs, ZNF808 and ZNF267. ZNF808 was found to be homozygous knock out in patients diagnosed with pancreatic agenesis, presenting neonatal diabetes with insufficient pancreatic exocrine function. Expression and ChIP data for ZNF808 show that it is …
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A TRIM28 centric strategy to efficiently uncover the contribution of KZFPs to the evolution of gene regulatory networks
… evidence in favour of this model; for example, ZNF808 has recently been identified as an essential primate-specific regulator of pancreas development via the regulation of MER11 elements which, when derepressed, are able to trigger a liver cell fate program. Here I present a new large-scale …