Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"ZNF384"”.
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Investigating the Role of ZNF384 Rearrangements in Acute Leukemia
<p>Chromosomal rearrangements involving ZNF384 are the defining lesion in 5% of pediatric and adult B-cell acute lymphoblastic leukemia and tumors are characterized by aberrant myeloid marker expression. Additionally, ZNF384 rearrangements are the defining lesion in nearly half of pediatric …
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Genetic Mechanisms of Transcriptional Regulation in Childhood Acute Lymphoblastic Leukemia
… discovered a new ALL subtype characterized of ZNF384-mediated chromosomal translocations, providing new insights into genetic heterogeneity in childhood ALL. However, the underlying mechanism by which these genetic variants contribute to the transcriptional regulatory circuitries of ALL is …
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Master regulators of neuronal maturation in NGN2 reprogrammed iPSC-derived iNeurons
… KO lines for the transcription factors CUX2, ZNF384, FOSL2, PATZ1 and ONECUT2 for further in-depth investigation. MEA analysis demonstrated notable impairments in iNeuron electrophysiology, while neurite and synaptic connectivity profiling revealed stunted neurite outgrowth and synapse …