Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"ZENK"”.
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Experience, neuroanatomical plasticity and expression of the immediate early gene ZENK in the visual cortex of weanling rats
This investigation combines anatomical and molecular approaches to determine if expression of a specific regulatory transcription factor correlates with morphological plasticity, using a model of experience-dependent plasticity.
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Dynamic Modulation of an Immediate -Early Gene in the Songbird Forebrain
… minutes of novel song playback induces the IEG zenk in regions of the auditory forebrain (caudomedial neostriatum (NCM) and caudomedial hyperstriatum ventrale (CMHV)). Three hours of playback leads to the stimulus-specific habituation of this gene response. Here I show that a brief stimulus (1.5 …
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Analysis of Immediate-Early Gene Expression in the Songbird Brain Following Song Presentation
… (IEG) was studied. The isolation of the canary ZENK homologue is described, an IEG that encodes a zinc-finger protein and which is highly sensitive to growth factors and depolarizing stimulation, including stimuli leading to LTP induction in the mammalian hippocampus. Two methods were used to …
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The Role of Gene Regulation in Neural Circuit Development: Studies in the Zebra Finch
… the responsiveness of an immediate early gene ZENK was measured from 20 days post-hatch (immediately prior to song learning) to adulthood (after learning is completed), following either singing or playback of tape-recorded song. No significant differences were observed in the patterns of …
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Complex Acoustical Feature Representation in the Zebra Finch Caudomedial Neostriatum (Ncm)
… and contextual (novel vs. familiar) nature of zenk activation as well as results from electrophysiological studies suggest an involvement of this auditory region in complex auditory processes. In this thesis, we present a primary analysis of the representational strategies available in the …
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Adaptive value and development of nest-building in Red Bishops (Euplectes orix)
… neural control of nest-building behaviour, using ZENK expression as a marker for forebrain activity. Large-scale screening of the forebrain was possible with a newly developed automisation of the analysis of ZENK expression.
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Inference of phylogenetic relationships in passerine birds (Aves: Passeriformes) using new molecular markers
… I investigated the recently introduced gene ZENK for its phylogenetic utility for passerine systematics in combination and comparison to three already established nuclear markers. My phylogenetic analyses of a comprehensive data set yielded highly resolved, consistent and strongly supported …
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Statistical and Biological Analyses of Acoustic Signals in Estrildid Finches
… finches. Importantly, immediate early gene (ZENK) expression was significantly higher in embryos and nestlings exposed to conspecific zebra finch songs than those exposed to silence. Although no other significant differences were found, our results suggest a trend with ZENK expression being …
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Is It Memory or Is It Death? Caspase-3 and Memory Formation
… song (as assessed using the habituation of the ZENK IEG response as an indicator of memory). I also have investigated the regulation (turning on and off) of caspase-3 in the neuron by the protein xIAP (x-linked inhibitor of apoptosis protein). Thus caspase-3, apparently, has an essential role in …
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Response Modulation by Single Units in the Auditory Neostriatum of Songbirds: Characterization of Responses and Their Relationships to Nuclear Gene Regulation in Adult and Juvenile Zebra Finches
… even in juveniles that had not yet developed the ZENK induction response. Thus, the initial habituation of electrophysiological responses is not by itself a sufficient trigger for IEG induction, but it may still be necessary. These results indicate dissociation between gross physiological activity …
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Mixing and dynamics of the Mediterranean outflow
… along two preferred isopycnals: 27.5 and 27.8 (Zenk 1975b). The spreading of the flow contains both a barotropic and baroclinic character. The average change in angle above and below the maximum velocity of the outflow is 8°while at the edges of the flow the average direction of the outflow …