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Showing 1 to 3 of 3 for “"Yra1"”.
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Characterization of the Association of mRNA Export Factor Yra1 with the C-terminal Domain of RNA Polymerase II in vivo and in vitro
… cerevisiae</italic>, the mRNA export protein Yra1 (ALY/REF in metazoa) has been shown to cotranscriptionally associate with mRNA and is thought to deliver it to the nuclear pore complex for export to the cytoplasm. Based on a previous proteomics screen, I hypothesized that Yra1 is a …
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Proteomic Identification of Histone Post-Translational Modifications Induced By Dna Double-Strand Breaks and Novel Proteins Involved In The Dna Damage Response
… degradation factor Def1, the mRNA export protein Yra1 and the HECT E3 ligase Tom1. Each of these proteins was required for resistance to radiomimetics. Yra1 and Def1 were required for DSB repair per se, while Sit4 was required for rapid inactivation of the DNA damage checkpoint after DSB repair. …
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Genetic, Biochemical, and Electron Microscopic Analysis of Components Involved in Transcription Coupled mRNA Export
… formed by the export factors Sub2 and Yra1, a previously unknown factor, Tex1, and the THO complex. Thus, the TREX complex couples transcription elongation and mRNA export. To further characterize the TREX, I analyzed the genetic interactions of two components of the THO complex, THO2 …