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Showing 1 to 1 of 1 for “"YpkA inhibitors"”.
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A Structural Basis for Host Cytoskeletal Disruption and Virulence by Yersinia Protein Kinase A
… species is the Yersinia protein kinase A, or YpkA, a multi-domain protein that disrupts the eukaryotic actin cytoskeleton. YpkA contains a Ser/Thr kinase domain whose activity modulates pathogenicity and a domain that binds to both Rac1 and RhoA of the Rho family of small GTPases. The crystal …