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Showing 1 to 1 of 1 for “"Yersinia pestis, vaccine development, plasminogen activator protease, Braun lipoprotein"”.
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Yersinia pestis CO92 mutant deleted for the genes encoding Braun lipoprotein and plasminogen activator protease: Characterization of a potential live-attenuated vaccine candidate
There is no FDA-approved vaccine against Yersinia pestis, the causative agent of bubonic and pneumonic plague. Since both humoral- and cell- mediated immunity are essential in providing protection to the host against plague, we developed a live-attenuated vaccine strain by deleting Braun …