Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Yeast two hybrid screening system"”.
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Effects of DFO-Induced Hypoxia on Key Signaling Mediators
… negatively regulate MOR gene expression using a yeast two-hybrid screening system. RT-PCR analysis revealed an increased in RACK-1 expression while a decrease in MOR expression under DFO treatment was observed. These results supported our recent finding that RACK-1 participates in the regulation …
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Engineering Estrogen Receptor-Based Gene Switches and a Superoxide Dismutase for Therapeutic Applications
… This dissertation describes the application of a hybrid directed evolution/rational design approach for the engineering of two different proteins with desirable properties. In the first example, stepwise saturation mutagenesis of functionally important protein sites and random point mutagenesis …