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Showing 1 to 2 of 2 for “"Ydj1"”.

  1. Studies to Characterize the Requirements for the Binding and Release of ERdj3, a Mammalian ER DnaJ Homolog, from Substrates

    … homologues but very different from domain II of Ydj1, was also essential for substrate binding. Recent studies have demonstrated that Hsp70s can interact <em>in vitro</em> with some but not all DnaJ proteins from different organelles or even different organisms. To better understand restrictions …

    tenn-hsc Repository record for Studies to Characterize the Requirements for the Binding and Release of ERdj3, a Mammalian ER DnaJ Homolog, from Substrates (opens in a new tab)

  2. Protein misfolding toxicity and inclusion formation in cellular models of neurodegeneration

    Protein misfolding characterizes most neurodegenerative diseases. Protein misfolding is the conversion of specific proteins from their normal, often soluble, and native three-dimensional conformation into an aberrant, often insoluble, non-functional conformation. Protein inclusions and aggregates …

    uwo Repository record for Protein misfolding toxicity and inclusion formation in cellular models of neurodegeneration (opens in a new tab)