Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"YMDD mutants"”.
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Factors affecting initial virologic response and emergence of resistant mutants after adefovir treatment in lamivudine resistant chronic hepatitis B patients
… fragment mass polymorphism analysis was used for YMDD mutant and adefovir mutant detection. RESULTS: After adefovir administration, IVR was observed in 31% patients with lamivudine resistance. Factors associated with IVR were HBeAg negativity (P=0.04) and presence of liver cirrhosis (P =0.04). …
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Emergence of Adefovir-resistant Mutants after Reversion to YMDD Wild-type in Lamivudine-resistant Patients
… to evaluate the effect of reversion to YMDD wild-type on emergence of adefovir (ADV)-resistant mutation and antiviral activity of ADV in lamivudine (LAM)- resistant patients during ADV monotherapy. We determined YMDD mutations and ADV-resistant mutations before and every 3 months during …