Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"YAP expression"”.
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HPV E6 inhibits E6AP to regulate epithelial homeostasis by modulating keratinocyte differentiation commitment and YAP1 activation
… E6AP-/- cells. Amongst the pathways identified, YAP target genes were activated by either E6 expression or E6AP depletion. This is confirmed by the analysis of YAP expression pattern in both monolayer cell culture and HPV-infected lesions. As the conserved binding partner of Alpha group HPV E6 …
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3D microtissue–derived human stem cells seeded on electrospun nanocomposites under shear stress: Modulation of gene expression
… as well. Here, we studied modulation of gene expression in human adipose–derived stem cells (ASCs) exposed to shear stress and/or after MT formation. Materials and methods Electrospun meshes of poly-lactic-co-glycolic acid and amorphous calcium phosphate nanoparticles (PLGA/aCaP) at a weight …
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Establishment of MITF and TAZ as major determinants of uveal melanoma
… pathway, which signals through PLCβ4-MAPK and YAP, whereas CM is primarily driven by activation of the MAPK pathway. It has been well established that CM tumors are dependent on MITF, the master melanocyte transcription factor. Here, in stark contrast, we establish that MITF serves as a tumor …
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Prognostic and Predictive Factors in Renal Cell Carcinoma /// Прогностични и предиктивни фактори при бъбречноклетъчен карцином
… имунохистохимичната експресия на Neuropilin и YAP. Neuropilin има роля на ко-рецептор при свързването на VEGF и неговите рецептори и така участва в процеса на ангиогенеза. Освен в ендотелните клетки той се експресира още и при клетки на имунната система и епителни клетки-бенигнени и туморни. …