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Showing 1 to 2 of 2 for “"Y522S"”.

  1. Neuronal Calcium Regulation and Cellular Stress in a Malignant Hyperthermia Disease Model

    Santiago, Jason2001

    … (MH). Recently, a mouse model of human MH (Y522S-RyR1) has been developed. In skeletal muscle, Y522S-RyR1 exhibits an increased sensitivity to activation resulting in Ca2+ leak, mitochondrial disorganization, and cellular stress. Although RyR1 expression is limited in the brain, the …

    denver Repository record

  2. Die Halothan-induzierte Kalziumfreisetzung in Skelettmuskelfasern eines Mausmodells der Malignen Hyperthermie und ihre Modulation durch das Membranpotential

    Mall, StefanUniversität Ulm

    ulm-diss Repository record