Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 90 for “"Y chromosome"”.
-
Sequence of the mouse Y chromosome
The mouse Y chromosome has been studied for over 50 years, from the early sex determination and immunological phenotypes attributed to it in the 1950s, to the several mouse Y permatogenic phenotypes and the sex ratio distortion phenotype that are still being studied today. However, even though the …
-
The Use of Y-Chromosome Profiles in Forensic Genetics
In forensic science, Y-STR testing is one of the most common tools used to interpret DNA typing results, specifically for human identification purposes (SWGDAM, 2014). With the complexity in DNA samples, not only can they be different from another individual, but each unique haplotype contains …
-
Isolation and Genomic Analysis of the Cetacean Y-chromosome
The male-specific mammalian Y-chromosome represents a powerful tool for studying malemediated gene flow and genome evolution. Here it was possible to identify 7 polymorphic microsatellites for the first time in an odontocete species, using a combination of cell culture, cytogenetics and molecular …
-
The human Y chromosome : gene content and chromosomal abnormalities
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1998.
-
Diverse outcomes of homologous recombination in the human Y chromosome
Mammalian sex chromosomes began diverging from an ordinary pair of autosomes roughly 300 million years ago. Inversions in the evolving Y chromosome sequentially suppressed recombination with the X chromosome. While pseudoautosomal regions in the human Y chromosome still participate regularly in …
-
The effects of natural selection on human Y chromosome amplicons
The Y chromosome is unique among the mammalian chromosomes: it determines sex, and is therefore normally present in a single copy, unlike all other chromosomes that can recombine with an identical homolog. These two facts have had profound effects on the fate of the Y chromosome, subjecting it to …
-
Y Chromosome Gene Kdm5D Epigenetically Drives Sex Differences In Colorectal Cancer
… are ill-defined and presumptively ascribed to X-chromosome genes and sex hormones. Such sex differences are particularly prominent in colorectal cancer (CRC) where men experience higher metastases and mortality. A murine CRC model, engineered with an inducible transgene encoding oncogenic mutant …
-
Attempts to isolate highly viable, morphologically normal, Y- chromosome-bearing bovine spermatozoa
… isolate highly viable, morphologically normal, Y-chromosome-bearing bovine spermatozoa. The column consisted of a 500 ml separatory funnel in which 26 ml of extended semen was layered on top of a discontinuous gradient of 4% BSA (60 ml) over 10% BSA (60 ml). Results indicated that the greatest …
-
A quantitative view of Y-chromosome gene expression across the human body
Human Y-chromosome genes have long been known to play pivotal roles in two biological processes--sex determination and spermatogenesis. Recent studies have uncovered evidence that Y-chromosome genes also perform important functions beyond the reproductive tract. Little is known about the roles of …
-
The Use Of Pyrosequencing For The Analysis Of Y Chromosome Single Nucleotide Polymorphisms
The potential value of the Y chromosome for forensic applications has been recognized for some time with the current work dedicated to Short Tandem Repeat analysis and Single Nucleotide Polymorphism (SNP) discovery. This study examined the ability of two different SNP analysis methods to determine …
-
A Novel Mathematical Model of the Trojan Y-Chromosome Strategy with Optimal Control
… is an even more diffcult problem. The Trojan Y Chromosome (TYC) eradication strategy is one control method. This method alters the female to male sex ratio by introducing sex reversed males called supermales. These sex reversed males can only produce male progeny. Mathematical models of this …
-
The analysis of Y chromosome polymorphisms in populations of the United Arab Emirates
Y chromosome markers can complement the use of autosomal markers, for example when a forensic scientist is confronted with a DNA mixture or needs to amplify male specific markers in paternity cases where the father is not available. Y chromosome markers are also powerful lineage markers and …
-
Physiological and Molecular Consequences of Large Y Chromosome Long Arm Deletions in Mice
The mammalian Y chromosome contains genes important for male sexual maturity and reproduction. The mouse Y chromosome long arm harbours a number of multi-copy genes whose absence or reduced representation has been linked to sperm defects and offspring sex ratio distortion in favour of females. …
-
Surname Distributions, Origins, and their Association with Y-chromosome Markers in the Aleutian Archipelago
… of surnames as well as their association with Y-chromosome haplogroups found in Native communities from the Aleutian Archipelago. The project's underlying hypothesis is that surnames and Y-chromosome haplogroups are correlated in the Aleutian Islands because both are paternally inherited markers. …
-
The Genetic Structure of the Kuwaiti and Failaka Island Populations: Y-chromosome & Mitochondrial DNA Variation
Recent studies applying multidisciplinary approaches suggest that the Anatomically Modern Homo sapiens (AMHS) passed through the Arabian Peninsula in their major diaspora out of Africa. The Arabian Peninsula is connected to three continents: Africa, Asia, and Europe. In addition to the major …
-
Molecular analysis of the sex-determining region of the Y chromosome in the platyfish Xiphophorus maculatus
… Xiphophorus maculatus has three types of sex chromosomes (X, Y and W; females are XX, WX or WY; males are XY or YY). Its gonosomes are at an early stage of differentiation. The sex-determining locus on the sex chromosomes is flanked by two receptor tyrosine kinase genes, the Xmrk oncogene and …
-
Centromere identification and inactivation on a neo-Y chromosome fusion in threespine stickleback fish (Gasterosteus aculeatus)
… are the primary constriction observed on many chromosomes, and they are required for normal cell division. Having one and only one centromere per chromosome is essential for proper chromosome segregation during both mitosis and meiosis. Chromosomes containing two centromeres (dicentric) often …
-
Y chromosome and allozyme correlates of geotaxis in selected lines of Drosophila melanogaster and their hybrids
… by polygenes located on each of the three major chromosomes (X, II, III), but the effect of the Y chromosome on geotaxis has not been studied. This study describes three experiments in which 12,604 flies were tested for geotaxis. In the first two experiments seven successive generations …
-
Finding the "Scot" in the Scottish-American: An Investigation of Scottish Identity through Mitochondrial DNA and Y-chromosome Markers
Individuals from Scotland began migrations to the Americas in the 1600s and, despite admixture, continue to celebrate their Scottish roots. Molecular markers were used to answer the following: 1) do individuals who claim a Scottish identity have maternal or paternal markers found in Scotland; 2) …
Page 1 of 5