Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Y RNAs"”.
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Origins of non-coding Y RNA family and its role in DNA replication
Y RNAs are a family of non-coding RNAs that are required for chromosomal DNA replication initiation in vertebrates. Specifically, Y RNAs play an essential role in the establishment of new DNA replication forks during G1 to S phase transition. However, the mechanism by which Y RNAs contribute to …
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Biogenesis of Y RNA–derived small RNAs
Small non-coding RNAs (sRNAs) constitute a significant portion of the transcriptome in eukaryotes. Many of these sRNAs regulate gene expression. Next-generation sequencing (NGS) has revealed a plethora of previously uncharacterised sRNAs with potential biological function, a number of which …
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The genome-wide analysis of the specification and activation of human chromosomal DNA replication origin sites
… to NGS. Additionally, the replication factors Y RNAs and Xenopus laevis Nucleosome Remodelling and histone Deacetylation (xNuRD) complex are essential for DNA replication initiation, but the mechanism(s) involved remain unelucidated. The precise mechanisms of DNA replication, and factors involved …
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The Modulation of Innate Immunity by Cellular and Viral Noncoding RNAs
… that endogenous and viral non-coding RNAs possess the ability to alter innate immunity and inflammatory responses. For example, endogenous non-coding RNAs can be recognized by pattern recognition receptors to trigger innate immune activation and inflammation. Many positive sense RNA …
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Quality checking and expression analysis of high-throughput small RNA sequencing data
… the cell-wide identi�cation of small non-coding RNAs (sRNAs) and to assess their regulation using di�erential expression analysis by comparing two or more di�erent conditions. During an analysis of a typical set of sRNA sequencing (sRNA-seq) libraries, a large variety of tools and methods are …