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Showing 1 to 10 of 10 for “"Xenon-129"”.
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Hyperpolarized xenon-129 production and applications
<p>Hyperpolarized 3He and 129Xe were initially developed and used in the nuclear physics community. Lately they are primarily used in Medical Resonance Imaging (MRI). Although first MRI polarized gas images were acquired using 129Xe, the research community has focused mostly on 3He, due to the …
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Structural and functional pulmonary imaging using hyperpolzarized xenon-129
<p>We describe applications of hyperpolarized 129 Xe to pulmonary imaging. Unique characteristics of this gas such as its polarizability and diffusibility in tissue allow probing important properties of the lungs. Three methods that study structure and function of the lungs, Chemical Shift …
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Cryptophane Derivatives as Gas Sensors and Hyperpolarized Xenon-129 Biosensors
… DERIVATIVES AS GAS SENSORS AND HYPERPOLARIZED XENON-129 BIOSENSORS Najat S. Khan Professor Ivan J. Dmochowski This thesis describes the progress in the development of cryptophanes for three different applications: encapsulation of noble gases, 129Xe NMR biosensing for cancer detection, and the …
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Hyperpolarized Xenon-129 Magnetic Resonance Imaging of Functional Lung Microstructure
<p>Hyperpolarized 129Xe (HXe) is a non-invasive contrast agent for lung magnetic resonance imaging (MRI), which upon inhalation follows the functional pathway of oxygen in the lung by dissolving into lung tissue structures and entering the blood stream. HXe MRI therefore provides unique …
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Fundamental studies and applications for the development of novel MRI contrast agents: Hyperpolarized xenon-129 and superparamagnetic iron oxide nanoparticles
… types of MRI contrast agents: hyperpolarized 129Xe gas and superparamagnetic iron oxide nanoparticles (SPIONs). The largest `Achilles' Heel' of MR techniques is their inherent lack of detection sensitivity due to the exceedingly small magnitude of the nuclear spins, giving rise to small …
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Using High-Powered, Frequency-Narrowed Lasers For Rb/129Xe and Cs/129Xe Spin-Exchange Optical Pumping To Achieve Improved Production of Highly Spin-Polarized Xenon For Use In Magnetic Resonance Applications
… spin polarization, such as `hyperpolarized' xenon-129. Hyperpolarized xenon can either be used as its own chemical sensor (due to its exquisitely sensitive chemical shift range), or the non-equilibrium polarization may be transferred from xenon to another molecule of interest (such as a …
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NMR mit thermischpolarisiertem und hyperpolarisiertem Xenon
… thermally polarized as well as hyperpolarized xenon have been performed.Several porous samples like catalysts and natural rubber have been investigated by thermally polarized xenon. Due to the fact, that the xenon chemical shift is correlated with the pore size of a porous material, changes in …
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Xenon NMR with spectroscopic, spatial, and temporal resolution
129Xe NMR has found many applications in material sciences and medicine because of two useful properties of Xenon atoms for NMR: the sensitivity to their environment due to their highly polarizable electron cloud, which results in a wide range of chemical shifts, and the ability of being …
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Investigation of Deformable Image Registration Based Lung Ventilation Mapping for Radiation Therapy Using a Hybrid Hyperpolarized Gas MRI Technique
… resonance imaging (MRI) using Helium-3 and Xenon-129 as imaging contrast. Recently, a new method has been proposed in which deformable image registration (DIR) is performed on a pair of anatomical lung images at different respiratory phases to obtain the displacement vector field (DVF) …
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Advanced NMR analysis of polymers and biomolecules
… wideline spectroscopy, and thermally polarized 129Xe has been investigated. Such a study using a combination of different advanced NMR methods was never reported before. A coherent picture that correlates the chemical sites and molecular dynamics resulted from this investigation. For the first …