Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"XRN1-resistant"”.
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Translation of Partially Decayed Messenger RNAs in Yeast
… that halt the progression of 5’→3’ exonuclease Xrn1. We show that these viral Xrn1-resistant structures (xrRNAs) can be used to protect specific homologously-expressed messenger RNAs from 5’→3’ degradation. We investigated the effects of addition of xrRNAs, artificially-installed into the …
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Point mutational examination of eukaryotic initiation factor 4E (eIF4E), inclusion bodies analysis, and Barley Yellow Dwarf Virus (BYDV) exonuclease resistant RNA structure mapping and prediction
… dwarf virus RNA (BYDV) that blocks exonuclease Xrn1 to generate BYDV subgenomic RNA3. Deletion analysis places the Xrn1 resistant (xrRNA) structure within the first 5’ 67 nucleotides of BYDV sgRNA3. Dianthoviruses, related to luteoviruses, have recently been shown to contain an xrRNA structure …
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Assessing and understanding the generation and function of RNA decay intermediates in non-insect borne flaviviruses
… major cytoplasmic cellular 5'-3' decay enzyme XRN1. In addition, members of the generas Hepacivirus, Hepatitis C Virus (HCV) and Pestivirus, Bovine Viral Diarrhea Virus (BVDV), possess XRN1 stalling elements within their 5' UTRs. These stalling sites block the action of the exonuclease and …