Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 48 for “"XDR"”.
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Molecular epidemiology, susceptibility profiles, outcomes and transmission dynamics in patients with extensively drug-resistant tuberculosis (XDR-TB) in two provinces of South Africa
… by drug-resistant tuberculosis (MDR-TB and XDR-TB), which has a high mortality, is a threat to health care workers, and is prohibitively costly to treat. MDR-TB has been supplanted by XDR-TB, resistance beyond XDR-TB, and programmatically incurable TB. Short-term treatment-related outcomes …
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Extensively drug-resistant tuberculosis in Africa: prevalence and factors associated: a systematic review and meta-analysis
… of extensively drugresistant tuberculosis (XDR-TB) in Africa. Although countries in Africa conduct national tuberculosis surveys on a regular basis, this information has not been systematically reviewed to ascertain the overall prevalence of XDR-TB in Africa. Methods: The study aimed to …
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Extensively drug resistant tuberculosis in South Africa
… for treatment-related outcomes in patients with XDR tuberculosis in settings with high HIV prevalence. We reviewed the case records of 227 consecutively diagnosed South African patients with XDR-TB between 2002 and 2008, and analysed the records of another 115 patients, retrospectively, for …
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The relationship between chest X-ray findings, bacterial load and treatment-related outcomes in persons with extensively drug resistant TB
… 2007. Extensively drug-resistant tuberculosis (XDR-TB), a more difficult and more expensive form of TB to treat with poorer outcomes, emerged in South Africa in 2006. The prevalence of XDR-TB is likely to be underestimated in South Africa as a result of incomplete detection and notification. In …
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Experiences of patients with extensive drug-resistant tuberculosis regarding prolonged isolation in a TB ward at a selected hospital in Namibia.
… of participants with Extensive Drug Resistance (XDR) regarding prolonged isolation. The participants with XDR-TB are admitted in isolation for a minimum of twenty (20) months in the hospital. Different factors contributed to the participants not adhering to the rules of isolation in the TB ward. …
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Development of an Autologous Human Dendritic Cell Vaccine against Mycobacterium tuberculosis in Patients with Extensively Drug-Resistant Tuberculosis
… Extensively drug-resistant tuberculosis (XDR-TB), and resistance beyond XDR-TB (often untreatable), is an increasing public health concern globally. Drug resistance has outpaced the drug development pipeline. Therefore, alternative immunotherapeutic approaches are urgently needed. In this …
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How fast can ASN.1 encoding rules go?
… Sun Microsystem's External Data Representation (XDR) and HP/Apollo's Network Data Representation (NDR). The sizes of the encoded values produced by each set of encoding rules are compared and several implementations are measured for code size and throughput. To help examine implementation issues, …
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Prevalence of Multidrug-Resistant Tuberculosis in Adults at University Teaching Hospital
… of MDR-TB and extensively drug-resistant (XDR) TB.MDR-TB is defined as a strain of that is resistant to at least Isoniazid and Rifampicin whether there is resistance to other drugs or not. XDR-TB is defined as resistance to at least rifampicin, isoniazid, a second line injectable …
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Prevalence of Multidrug-Resistant Tuberculosis in Adults at University Teaching Hospital
… of MDR-TB and extensively drug-resistant (XDR) TB.MDR-TB is defined as a strain of that is resistant to at least Isoniazid and Rifampicin whether there is resistance to other drugs or not. XDR-TB is defined as resistance to at least rifampicin, isoniazid, a second line injectable …
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Microbiological, genomic and transcriptomic analyses of human tuberculosis lung cavities
… and extensively drug-resistant TB (MDR- and XDR-TB) patients scheduled for therapeutic lung resection surgery in Cape Town were prospectively recruited. Biopsies were obtained from specific positions in and around cavities. Drug-susceptibility testing, strain-type determination, whole-genome …
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Three-Dimensional (3D) pharmacophore-based identification of possible ATP-synthase inhibitors for mycobacterium tuberculosis (Mtb)
… Rifampicin, while extensively drug resistant (XDR-TB) includes resistance to fluoroquinolone as well as other second- line drugs (Capreomycin, Kanamycin and Amikacin). Bedaquiline (BDQ) is a diarylquinoline aimed at inhibiting the adenosine triphosphate (ATP) synthase of MDR-TB, thereby …
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Acceptability of Oral Immunization Against Cholera and Typhod Fever among School Children in Lusaka
… of MDR-TB and extensively drug-resistant (XDR) TB. MDR-TB is defined as a strain of Mycobacterium tuberculosis that is resistant to at least Isoniazid and Rifampicin whether there is resistance to other drugs or not. XDR-TB is defined as resistance to at least rifampicin, isoniazid, a …
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Acceptability of Oral Immunization Against Cholera and Typhod Fever among School Children in Lusaka
… of MDR-TB and extensively drug-resistant (XDR) TB. MDR-TB is defined as a strain of Mycobacterium tuberculosis that is resistant to at least Isoniazid and Rifampicin whether there is resistance to other drugs or not. XDR-TB is defined as resistance to at least rifampicin, isoniazid, a …
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Physiologically-Based Pharmacokinetic (PBPK) Modeling for the Preclinical Development of Spectinamide Antibiotics
… (MDR) and extensively drug-resistant (XDR) cases, the treatment for TB with the standard first and second-line therapy is becoming increasingly difficult. Therefore, there is an urgent need to find new anti-TB drugs as combination partners of existing and experimental classes of …
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Outcomes of patients undergoing lung resection for drug-resistant TB and the prognostic significance of pre-operative positron emission tomography/computed tomography (PET/CT) in predicting treatment failure
… anti-TB drugs almost a third of patients with XDR-TB have unfavourable outcomes. In patients with localised disease and adequate pulmonary reserve, surgery is an important adjunctive treatment. However, there are no outcome data from TB endemic countries, and the prognostic significance of …
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Prevalence of drug-resistant tuberculosis and associated risk factors among patients in the Northern Region of South Africa
… (MDR-TB), pre-extensively drug-resistant TB (pre-XDR-TB) and XDR-TB. Globally, about 465,000 people have rifampicin-resistant TB (RR/TB; 78% MDR-TB), where new cases contribute about 3.5%, and 18% among previously treated cases. Variety of factors, including demographic, behavioural, clinical, and …
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Factores de virulencia de Pseudomonas aeruginosa de origen clínico, animal, alimentario y ambiental
… se clasificaron como modR, un 18% MDR y un 3% XDR, mostrando diferentes fenotipos de resistencia en función del origen. El serotipo no tipable (30%) fue el más frecuente, siendo más prevalente en las cepas de origen clínico, seguido de O:6 (19%), O:1 (12%), O:3 y O:11 (8% cada uno). Se demostró …
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OODSF: an object-oriented data specification framework in a heterogeneous computing environment
… of the OODSF contains external Encoding Rule (XDR) and Basic Encoding Rule (BER).
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Syntéza a hodnocení potenciálních antimykobakteriálních látek odvozených od hydrazinu
… even exhibit some activity against MDR- TB and XDR-TB strains.
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Antimycobacterial, docking and molecular dynamic studies of pentacyclic triterpenes from Buddleja saligna leaves
… and extensively drug-resistant M. tuberculosis (XDR-TB) using the Micro Alamar Blue Assay. Ursolic acid was isolated from this plant for the first time.
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