Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Wolfram syndrome"”.
-
The development of diabetes mellitus, fertility and energy metabolism disturbances in a Wfs1-deficient mouse model of Wolfram syndrome
Wolframi sündroom (WS) on autosoom-retsessiivse pärandumismustriga neurodegeneratiivne haigus, mille peamisteks kliinilisteks avaldusteks on varases lapseeas algav 1. tüüpi diabeet, nägemisnärvi atroofia, magediabeet ja sensorineuraalne kuulmislangus. Lisaks võivad esineda ka urotrakti väärarendid, …
-
Molecular and Functional Characterization of Pyramidal Cell Types in the Frontal Cortex of Mouse Brain
… to the complex neurological disorder, Wolfram Syndrome. Therefore, a combination of specific gene driver selection, BAC transgenesis methods and functional modulatory strategies can give us valuable insight into the underlying neuronal circuitry in the cortex responsible for distinct …