Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Wnt5a expression"”.
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The Role of The Hypoxia-Inducible Factor 2 In Pancreatic Cancer: Mechanisms of Tumor Immunosuppression and Intestinal Radioprotection
… HIF2 in SI organoids and found that <em>Wnt5a </em>was among the top upregulated transcripts. Luciferase reporter assays showed that HIF2 directly activates the <em>WNT5A </em>promoter via a hypoxia response element. Furthermore, through knockout and rescue experiments, we found that …
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Untersuchungen zur Rolle von Wnt5a beim Basalzellkarzinom
… Ptch zurückzuführen ist. Daneben scheint auch Wnt5a eine Rolle bei diesem Tumor zu spielen, da eine Überexpression dieses Gens beim BCC beschrieben worden ist. Ziel dieser Arbeit war es, eine mögliche Regulation von Wnt5a durch die Hh/Ptch-Signalkaskade, den Effekt von Wnt5a auf Keratinozyten …
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Macrophage Polarization (M1/M2) and its Role in Wnt5a Secretion/Expression in Atherosclerosis
… atherosclerotic lesions has been suggested. Wnt5a is a noncanonical member of the wingless family of proteins that is expressed in human macrophages in different inflammatory diseases including atherosclerosis. These observations led us to hypothesize that Wnt5a secretion/expression is …
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Genistein suppresses colon cancer metastasis through epigenetic regulations
… addition to NDRG1, dramatic down-regulation of Wnt5a, one of the WNT signaling factors, was also found in SW620 compared to SW480. Wnt5a expression was not responsive to DNA methyltransferase inhibitor 5-aza-cytidine treatment. However, histone deacetylase (HDAC) inhibitors trichostatin A (TSA) …