Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Wnt antagonist"”.
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Anteriore Musterbildung im Wirbeltierembryo - Die Induktion von Vorderhirn und Herz
… bisher im Huhn noch nicht bekannte, sekretierte Wnt-Antagonist cSzl, der im zweiten Teil der Arbeit charakterisiert wurde. cSzl ist im anterioren Endoderm und in der Herzanlage vom Stadium HH4 bis zum Stadium HH25 exprimiert und markiert dort den anterioren Pol des Herzschlauches. cSzl wird von …
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Activin signaling controls a wound-induced program essential for regenerative patterning
… mechanisms that specify what to regenerate. The Wnt antagonist gene notum is induced within hours after injury robustly at anterior-facing wounds preferentially, where it specifies head regeneration. We report that Activin signaling is required for regeneration polarity, and the underlying …
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Der Wnt-Signalweg in der Makrophagen-induzierten Invasion von Brustkrebszellen
… Aspekt der Tumorbiologie dar. Die Familie der Wnt-Signalproteine ist ein potentieller Mittler dieser Kommunikation. Anhand des Expressionsmusters von Wnt-Rezeptoren, -Liganden und Zielgenen konnte ein Wnt-sensitiver Phänotyp in Tumorzellen und Makrophagen identifiziert werden. Die Ko Kultur von …
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Wnt Secretion Proteins Modulate RANKL-Induced Expression of Aire in Thymic Epithelial Cells
… In the thymus, TECs differentially express Wnt proteins, which activate canonical and non-canonical Wnt signaling pathways. Wnt signaling is thought to regulate cell survival, proliferation, and development although the direct molecular mechanisms in TECs have yet to be elucidated. The …
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The roles of FGF and Wnt signaling during maxillary barbel regeneration in the Zebrafish (Danio rerio).
… Fibroblast growth factor (FGF) and wingless (Wnt) signaling are required for the control of zebrafish caudal fin regeneration; due to the similarities between the fin and the maxillary barbel, these regulatory networks may play a role in barbel regeneration as well. In this study, I explored …
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Wnt Inhibitory Factor (WIF)-1 Promotes Melanogenesis in Normal Human Melanocytes
Background: Wnt inhibitory factor-1 (WIF-1) acts as a suppressor of Wnt antagonists. There is no study available on melanogenesis effect of human melanocytes. Objectives: In this study, we investigated the expression of WIF-1 in human melanocytes and the effects of WIF-1 on melanogenesis. Method: …
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Epigenetic modifications on WNT genes by dietary genistein during colon cancer development
… that genistein restored the expression of a Wnt antagonist sFRP2, which was silenced in colon cancer cells, by affecting the DNA methylation at the promoter of the gene. Consequently, the abnormally activated Wnt signaling was attenuated, leading to repressed cancer cell viability and …