Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Within Host Dynamics"”.
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Drivers of Dengue Within-Host Dynamics and Virulence Evolution
… chapter of my dissertation, I integrate these within-host models with a vector-borne epidemiological model to understand the potential for virulence evolution in dengue. Critically, I show that dengue is expected to evolve towards intermediate virulence, and that the optimal virulence of the …
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Integrating mathematical models with experimental data from in vivo studies to investigate the within-host dynamics of Salmonella Typhimurium
… innovation in the field is by understanding the host-bacteria interactions that take place in vivo and affect the clinical outcome of the disease, the response to treatment and the immunological response following vaccination. Mechanistic mathematical models are being increasingly used to advance …
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Mathematical modeling, analysis, and simulation of Cholera dynamics
… multiple models to investigate the transmission dynamics of cholera. At first, we consider the intrinsic growth of cholera bacteria in cholera transmission and find that the regular threshold dynamics take place if the intrinsic growth is logistic; there are multiple endemic equilibria if the …
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Multi-scale and multi-group modeling techniques applied to Cholera and COVID-19
… infection with the Vibrio cholerae bacteria. The dynamics of the disease transmission are governed by human-human, environment-human, and within-human sub-dynamics. Specifically, the within-host dynamics incorporate virus and immune cell interaction with the vibrios. One model is presented to …
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Contraction Analysis of Functional Competitive Lotka-Volterra Systems: Understanding Competition Between Modified Bacteria and Plasmodium within Mosquitoes.
… resource limitation and immune response of a host due to infection. We name this new system a Functional Competitive Lotka-Volterra (FCLV) model. We mainly use the construction of contraction metrics, to determine global properties of the model. We use this result to analyze the competition …
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Within-host population dynamics and collective interactions of SARS-CoV-2 and influenza virus
… genetically distinct viral genomes interact within a cell. Because every virus that circulates within a host population must initially emerge within a single individual, it is crucial to understand the factors that govern viral dynamics within a host. Intra-host viral populations are subject …