Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Whole-genome expression"”.
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mRNA EXPRESSION ANALYSIS OF MIDBRAIN DOPAMINE NEURONS IN RESPONSE TO NICOTINE INTAKE DURING MATURATION
… and memory. Previous studies suggested that the expression of neuroprotective genes was significantly different in the VTA and SN dopamine neurons and nicotine mediated neuroprotection in PD. These studies encouraged us to investigate how nicotine changes the expression of these differentially …
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Heat stress: A risk factor for skin carcinogenesis
… controls. Cell proliferation, apoptosis and whole genome expression profiles were analysed at four hours post day 4 exposure, to understand earlier events, and at 2 days post-exposure, to assess persistent outcomes of these exposures. Treated primary NHEK cells were counted in a Vi-CellTM …
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Analysis of gene expression alterations in premalignant progression from normal mammary epithelium to ductal carcinoma in situ by multiple orthogonal tools
… goal of the present study was to determine gene expression changes in different DCIS models (MCF10.DCIS, SUM102 and SUM225) in comparison to normal breast epithelial cells (MCF10A) that may enable us to identify novel markers of disease progression and potential therapeutic targets. We cultured …
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Food processing modulation on breast cancer
… controls received sham pellets. GeneChip Human Genome U133 Plus 2.0 Array platform was used to evaluate gene expression, and results were analyzed using bioinformatics approaches. Tumors in MS-fed mice exhibited higher expression of tumor growth suppressing genes ATP2A3 and BLNK, and lower …
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Genetic Exploration of Hereditary Immune Diseases
… the human body. The mutated genes cause the gene expression levels to change which fail to properly regulate the body's functions, resulting in immune system diseases. I used existing mouse models to improve the understanding of these two diseases.</p> <p>The first study concerns Arthritis …