Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Whole genome amplification (WGA)"”.
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Virtual microfluidics : a novel single-cell technology based on diffusion-restricted reaction that makes high-quality low-input genomic research accessible
… the smallest unit of life and amplify single genomes for sequencing. Current single-cell technologies require complex instrumentation and the data quality is often confounded by biased genome coverage and chimera artifacts. We address these challenges with a new single-cell technology paradigm …
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Improving genome assembly by identifying reliable sequencing data
De novo Genome assembly and k-mer frequency counting are two of the classical prob- lems of Bioinformatics. k-mer counting helps to identify genomic k-mers from sequenced reads which may then inform read correction or genome assembly. Genome assembly has two major subproblems: contig construction …
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DNA profiling of single sperm cells and single skin flakes in forensics using micromanipulation and whole genome amplification.
… cells and skin flakes. After studying multiple whole genome amplification (WGA) protocols, REPLI-g Single Cell WGA was selected due to its suitability in the pre-amplification step of template DNA. Micromanipulation was used to isolate single spermatozoa. Furthermore, micromanipulation in …
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Short tandem repeat (STR) profile authentication via machine learning techniques
… using standard laboratory techniques such as whole genome amplification and molecular cloning. Such technologies can be used to synthesize any STR profile without the need for a physical sample, only knowledge of the desired genetic sequence. Therefore, to preserve the credibility of DNA as a …