Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 81 for “"White blood cells"”.
-
Identification and validation of Biomarkers for Breast Cancer from human White Blood Cells
… treatment efficacy of breast cancer. Peripheral white blood cells (WBCs) carrying the information related to the presence of cancer, represent an attractive source for novel biomarkers. The main aims of the study were to develop the pipeline to discover and validate novel biomarkers in WBCs of …
-
The role of platelets and leukocytes in endogenous fibrinolysis.
… aggregation of circulating platelets and white blood cells on the plasma activity of t-PA and PAI-1 was measured. In vivo platelet and white blood cell aggregation was induced by platelet and white blood cell agonists, the effect being monitored by the Technicon autocounter. Plasma …
-
DNA damage and repair during the mammalian hormonal cycle
… especially so when surrogate tissue such as white blood cells are involved. Because certain factors including gender, age and diet may influence the comet assay responses in lymphocytes when monitoring human genotoxicity, we posed the question whether the menstrual cycle would influence the …
-
Microfluidic sensor for white blood cell counting and flow metering
… tests recommended by the physicians is Complete Blood Cell Count (CBC). For example, there is a decrease in the platelet count in case of Dengue fever. Red blood cells decrease in the case of anemia. CD4 T cells decrease in the case of HIV/AIDS. Cell counting in general, and ability to count the …
-
Polyunsaturated Fatty Acids and the Epidermal Growth Factor Receptor/ Mitogen- Activated Protein Kinase Signal Transduction Cascade in Mammary Cancer
… MAPK levels can be detected in both peripheral white blood cells (WBC) and mammary adipose tissue in cats. Adipose tissue levels of active MAPK were similar to those observed in peripheral WBC, suggesting that WBC MAPK might serve as a useful biomarker in the diagnosis or follow-up treatment of …
-
Influence of randomness in mathematical models for diffraction and T-cell recognition
… recognition of foreign invaders by certain white blood cells.
-
An investigation of centrifugal blood-cell separation
… the centrifugal, batch separation of whole blood into subpopulations of red blood cells (erythrocytes) and white blood cells (leukocytes). Separations took place in a custom-built centrifuge (using a seal-less, anti-twisting feed/withdrawal system) containing, a 25-ml capacity separation …
-
Stochastic dynamics of cell adhesion in hydrodynamic flow
… for this work is the rolling adhesion of white blood cells experimentally investigated in flow chambers. There, specific adhesion is mediated by weak bonds between complementary molecular building blocks which are either located on the cell surface (receptors) or attached to the bottom …
-
IL-1β Amplification of Nitric Oxide Production and Its Inhibitory Effects on Glucose Induced Early Growth Response-1 Expression in INS-1 Cells
… of cytokines released by infiltrating white blood cells upon pancreatic beta cells is not fully understood. Early growth response gene-1 (Egr-1) expression is specifically and transiently up regulated in pancreatic beta cells in response to glucose. We hypothesized that interleukin-1 …
-
Reproducibility and reliability of chromatin immunoprecipitation in clinical research
… results in a clinical population using white blood cells. It was established, for the first time, the normal variability of ChIP results in THP-1 cells, Jurkat cells, TF-1a, and human male circulating leukocytes over time for histone modifications H3k4me3 and H3k9Ac.</p>
-
Some observations of the diurnal variations in leucocyte count in man, with special reference to the effect of digestion: being a record of 37 experiments
… renders the knowledge of the variations of the white blood cells under normal physiological conditions necessary, for without this knowledge our interpretation of the result of a leucocyte count does not rest on a sound basis and may be erroneous. Although some aspects of physiological increase …
-
Developement of Natural Multifunctional Cosmetic Ingredients Using Biotechnological Approach
… reactive oxygen species production by human white blood cells was used as a marker for immunological activity of GFEPS. Antioxidant assays revealed a considerable scavenging activity upon peroxynitrite and superoxide, suggesting that GFEPS is a freeradical scavenging agent. In addition, it …
-
Parasitic infections and storage iron deficiency in children in improverished regions of Mauritius
… plasma ferritin, haemoglobin concentration, white blood cells count, packed cells volume and blood group. It was found that there is a negative correlation between the number of parasites and haemoglobin concentration, packed cells volume of blood and degree of infestation, number of …
-
Using convolutional neural networks for fine grained image classification of acute lymphoblastic leukemia
… leukemia (ALL) is a cancer of bone marrow stems cells that results in the overproduction of lymphoblasts. ALL is diagnosed through a series of tests which includes the minimally invasive microscopic examination of a stained peripheral blood smear. During examination, lymphocytes and other white …
-
A universal miniaturized electrochemical sensing platform and its applications
… nitrate concentration and counting number of white blood cells. This inexpensive, portable device is also suitable for a variety of other applications, ranging from instant food/water quality examination to long-period environmental monitoring. We tested this lab-on-chip sensing platform under …
-
Radioimmunotherapy of Metastatic Disease - Studies of Alpha- and Beta-particle-Emitting Radionuclides in a Preclinical Model
… toxicity was deemed tolerable as the numbers of white blood cells and platelets recovered to initial levels. Administration of the minimal effective activity of 177Lu-mAbs followed by treatment with unlabeled mAbs, 177Lu-mAbs, or 211At-mAbs resulted in a small increase in the number of tumors …
-
The Role of the ITAM-containing CEACAM3 Receptor in the Neutrophil Response to Infection by Neisseria gonorrhoeae
… a massive influx and activation of neutrophils, white blood cells involved in the early/innate immune response to pathogens, at the infection site. Neisseria spp. bind to and activate neutrophils via their Opacity-associated (Opa) outer membrane proteins, which interact with some members of the …
-
The Effects of Leucogenenol On Benzene Induced Bone Marrow Suppression In Rabbits
… stimulated by leucogenenol, in an animal whose white blood cells have been reduced by the action of benzene. Procedure. The white blood cell counts of rabbits were depressed to 1500 ± 500 cells per cubic millimeter by the action of benzene. At this time the animal, depending upon the grouping, …
-
Phagocytosis by neutrophils - studies on phagosome dynamics and membrane traffic modulation by Streptococcus pyogenes
Neutrophils are our most numerous and deadly white blood cells and without them we would succumb quickly to infections by pathogens. The main mechanism that the neutrophils employ for our protection is phagocytosis, where they eat and enclose their target inside a membrane-bound organelle, the …
-
Nutrition parameters predicting functional status decline in the older adult
… hemoglobin, and percent lymphocytes and white blood cells (to calculate total lymphocyte count) were measured; fat reserves and somatic protein were estimated from anthropometry; and physical signs of malnutrition and a composite of nutritional status indicators were assessed. The …
Page 1 of 5