Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"Wheezing"”.
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A Theory for Wheezing in Lungs
A quarter of the world's population experience wheezing. These sounds have been used for diagnosis since the time of the Ebers Papyrus (ca. 1500 BC), but the underlying physical mechanism responsible for the sounds is still poorly understood. The main purpose of this thesis is to change this, …
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Association of Faecalibacterium, Lachnospira, Veillonella, and Rothia with childhood wheezing
Wheezing symptoms among children, present major health and economic problems globally. A recent study conducted in Canada observed a reduction in stool bacterial genera Faecalibacterium, Lachnospira, Veillonella and Rothia (FLVR) in three-month old infants with atopy-wheeze symptoms. It is not …
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The stool microbiota and infant wheezing illness - the Drakenstein child health study, South Africa
Background: Wheezing is one of the leading respiratory symptoms in childhood, which with recurrent occurrence can lead to asthma at school age. Few studies, with conflicting findings, have investigated the contribution of stool bacteria in childhood wheezing illness. Additionally, most of the …
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Multi-state models for the analysis of Wheeze in a birth cohort of Western Cape children
Introduction Wheezing is common in young children. By the age of six, approximately 50% of children in high-income countries will have experienced at least one episode of wheezing in their life. Furthermore, childhood wheezing may be associated with reduced lung function and increased risk of …
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Latent class modelling of respiratory outcomes in a South African birth cohort
… on two key respiratory outcomes: childhood wheezing and lung function. It examines (1) the underlying heterogeneity of wheezing and lung function measurements through the derivation of latent phenotype classes and (2) the impact of early-life lower respiratory tract infections (LRTIs) and …
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The epidemiology of asthma and wheeze in primary school children in Mitchell's Plain, Cape Town, with special reference to the role of environmental tobacco smoke
… were asked: 1) is the prevalence of asthma and wheezing in primary school children? (2) What is the reliability (across two questionnaires) of questions about wheezing and asthma? 3) What are the household risk factors for wheezing and asthma; in particular, to what extent is household …
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Long-term effect of respiratory syncytial virus (RSV) infection on children: a prospective longitudinal birth cohort study in Bangladesh
… are at increased risk for asthma and recurrent wheezing in subsequent years. Nevertheless, few studies have assessed the long-term impact of RSV infection in developing healthcare settings, and none of the previous studies focussed on neonates. This PhD thesis aimed to evaluate the long-term …
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Quality of Life and Health Outcomes in Overweight and Non-Overweight Children with Asthma.
… (ED) visits, hospitalizations, number of days wheezing, number of night wakings and spirometry values. QOL was measured using the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). The obese group reported the highest percentage of ED visits, hospitalizations, and number of days wheezing …
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Indoor air pollution and environmental tobacco smoke exposure in a South African birth cohort study
… on child health and lung diseases, LRTI and wheezing illness in the first year of life. To measure exposures comprehensively, two home visits, one in the antenatal period (third trimester) and the second postnatally (between 4 and 6 months of the infant’s life), were conducted to assess the …
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An assessment of dust exposure levels and factors associated with the occurrence of respiratory symptoms among workers in the road construction industry in Lusaka, Zambia
… symptoms was nose irritation (59.3%), wheezing (45%) phlegm 29% and shortness of breath (39.3%).The mean respirable dust exposure level was 1.768mg-yr/m3. Exposure to a cumulative respirable dust concentration of ≥1.768mg-yrs/m3 was significantly associated with shortness of breath (OR …
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An assessment of dust exposure levels and factors associated with the occurrence of respiratory symptoms among workers in the road construction industry in Lusaka, Zambia
… symptoms was nose irritation (59.3%), wheezing (45%) phlegm 29% and shortness of breath (39.3%).The mean respirable dust exposure level was 1.768mg-yr/m3. Exposure to a cumulative respirable dust concentration of ≥1.768mg-yrs/m3 was significantly associated with shortness of breath (OR …
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Characterization of Human Airway Epithelial to Mesenchymal Transition upon Rhinovirus Infection
Human rhinovirus (HRV)-induced wheezing illnesses in early life are a major risk factor for subsequent asthma development, and may contribute to induction and progression of airway remodeling (AR) seen in the airways of asthmatic subjects. Thickening of the lamina reticularis is a component of AR …
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Mathematical Modeling and Analysis of Asthma Stability and Severity
… whites. People with asthma experience attacks of wheezing, breathlessness, chest tightness, and coughing. Asthma can be fatal and the costs for the disease (direct and indirect) are approximated to be tens of billions of dollars each year.</p> <p>There is no cure for asthma. However; for most …
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A prospective cohort study on ambient air pollution, airborne pollen (and fungal spores) and respiratory morbidities including childhood asthma in adolescents from the Western Cape Province
… them were on asthma treatment. The prevalence of wheezing in the past 12 months (12.9%), airway obstruction (17.6%) and airway inflammation (10.2%) was much higher. The presence of damp conditions, visible mould growth, passive smoking as well as paraffin-use for cooking and heating were …
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A Descriptive Analysis of Tobacco Use Policies Among Select Family Day Homes in Virginia
… to secondhand smoke can cause coughing and wheezing, bronchitis, pneumonia, ear infections, asthma, and sudden infant death syndrome (SIDS). Childhood exposure to ETS may also increase the risk of developing leukemia and lymphoma in childhood (Mitchell, 1997) as well as developing lung …
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Spatial Patterns and Correlates of Lower Respiratory Tract Illnesses in Children from Drakenstein, Western Cape
… there was some variation in the density of wheezing cases in comparison to controls. In particular, there was evidence of a non-random difference in the distribution between cases and controls, and cases of wheeze were significantly more concentrated the TC Newman area than expected. Those …
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TRAIL and TGF-ßl-Induced Apoptosis of Human Airway Epithelial Cells
… hyperresponsiveness (AHR), airway obstruction, wheezing, and leads to airway remodeling if these symptoms persist. Airway remodeling is characterized by goblet hyperplasia, airway smooth muscle hypertrophy and hyperplasia, subepithelial fibrosis and denudation of the epithelium. Due to weakened …
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The association between ambient air pollution and cardiorespiratory health outcomes of adults residing in informal settlements of the Western Cape in a 12 month period
… household. Cardio-respiratory outcomes included wheezing in the last 12 months, doctor diagnosed asthma, asthma symptoms score (calculated as the sum of positive responses to 3 asthma questions), chest pain, hypertension and hypercholesterolaemia. The quantile g computation package in R was used …
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Determining the Effects and Signaling Properties of β-Blockers in House Dust Mite-Driven Murine Models of Asthma
… clinical symptoms such as recurrent coughing, wheezing, chest tightness, and shortness of breath. As often patients require life-long management of these symptoms, health care costs associated with asthma management are continually increasing, particularly in developed countries such as the …
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Efficacy of oral corticosteroids for preschool wheeze
… (OCS) have been widely used to treat acute wheezing episodes in clinical practice, evidence has been contentious regarding the efficacy of OCS for preschool wheeze. This thesis aims to assess the OCS treatment in treating acute preschool wheeze by incorporating perspectives of health …
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