Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 47 for “"Wheel running"”.
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Examination of voluntary wheel running on markers of adipose thermogenesis in intact and ovariectomized female mice
… aimed to investigate the effect of voluntary wheel running (VWR) in ovariectomized (OVX) mice on whole body energy expenditure and body composition, key protein markers of thermogenesis and adipose tissue browning, and fluctuations in circulating and AT BDNF and receptor content. It was …
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The Effects of Resistance Wheel Running on Skeletal Muscle Function and Adaptation in C57BL/10SnJ Mice
Background: Resistance wheel running (RWR) can promote resistance-like training adaptations in mouse skeletal muscle (SkM), but its endurance-training effects are lesser known. Methods: Voluntary RWR was modulated as an exercise model to increase mouse hind-limb plantar-flexor torque and to promote …
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Voluntary wheel running mitigates hyperglycemia-induced depressive-like behavior and increases hippocampal BDNF levels in male mice.
… mice in the exercise group had voluntary running wheel access in their home cage for 6 weeks. As anticipated, STZ induced depressive-like behavior. Exercise attenuated behavioral deficits in the forced swim and splash test. Tissue analyses found that exercise affected hippocampal …
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Effects of voluntary wheel running and forced treadmill running on inflammation induced behavioral abnormalities in young and old mice
… was to investigate the effects of voluntary wheel running and forced treadmill running on lipopolysaccharide (LPS) and Bacillus Calmette-Guérin (BCG) induced sickness behavior (food intake, fluid intake, body weight, locomotor activity), depressive-like behavior (tail suspension test, sucrose …
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Effects of the gut microbiota and dietary inulin on age associated inflammation, endurance training adaptations, and voluntary wheel running motivation
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-12-04 without embargo terms
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The Majority of the Diaphragm Immune Transcriptome Profile Rescued in Mdx Mice by Microdystrophin Gene Therapy was maintained by Voluntary Wheel Running
… microdystrophin gene therapy with and without running wheel activity. Mdx mice are a model of Duchenne Muscular Dystrophy (DMD). Similar to DMD, mdx pathophysiology is associated with chronic inflammation due to sarcolemma fragility and cellular membrane leakage. Immune modulation has not yet …
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Estradiol exerts activational and organizational control over the expression of daily and circadian activity rhythms in mice
… on the expression of daily and circadian wheel running rhythms in female mice. Simultaneously, I will further elucidate the estrogen receptor-dependent mechanism(s) underlying these functional effects (Chapter 2). Second, I will examine the impact of developmental estradiol on adult daily …
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Ovarian hormones, but not androgens, mediate running-induced changes in high fat diet choice patterns in rats
… a two-diet choice (chow vs. HF) and voluntary wheel running paradigm found that upon simultaneous introduction of a novel HF diet and wheel running, male rats show complete and persistent HF diet avoidance whereas the majority of females reverse HF diet avoidance. Ovariectomy (OVX) appears to …
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Self-Control Choices Using Running Reinforcement
… the delivery of a smaller, immediate access to a running wheel (Impulsive) while responding on the other lever resulted in the delivery of larger but delayed access to a running wheel (Self-control). A variable inter-trial-interval was used to control the session duration regardless of the …
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Self-Control Choices Using Running Reinforcement
… the delivery of a smaller, immediate access to a running wheel (Impulsive) while responding on the other lever resulted in the delivery of larger but delayed access to a running wheel (Self-control). A variable inter-trial-interval was used to control the session duration regardless of the …
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An experimental analysis of the classic overjustification effect in rats: Does the removal of “expected” rewards alter behavior in rats as it does in humans?
… delivery controlled for. Baseline “intrinsic” wheel-running rates of seven SpragueDawley rats were compared to rates that followed administration and withdrawal of a contingent sucrose reward, and to rates of rats in control conditions (n = 7). Consistent with the author’s hypothesis, the …
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Effects of exercise and phytoestrogens on white adipose tissue health in estrogen deficient rodents
… underlying mechanisms to determine how voluntary wheel running (Chapter 3) or a diet rich in phytoestrogens (SOY) (Chapter 4) can improve WAT health following OVX in rodents. Female OVX rats selectively bred for high (HCR) or low (LCR) intrinsic aerobic capacity were fed a high fat diet (HFD; 45%) …
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The Effects of Chronic Stress and Exercise on Mouse Pancreatic Islet of Langerhans Morphology and Muscle Atrophy Gene Expression
… of chronic stress in combination with voluntary wheel running on murine islet morphology and skeletal muscle atrophy. The purpose of this study was to evaluate the effects of chronic stress and voluntary wheel running on murine beta cell number per Islet, insulin positive area in the pancreas, …
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Rats selectively-bred for low and high voluntary running: co-selected traits and the effects of voluntary running on the dentate gyrus transcriptome
… rats for low (LVR) and high (HVR) voluntary running behavior as a model for examining the genetic and physiological origins of physical activity motivation. The major advantage of selective breeding over non-natural methods of genetic engineering is the perpetuation of naturally-existing, …
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Identifying and Predicting Rat Behavior Using Neural Networks
… of neurons in the hippocampus, to a T-maze, wheel running or open exploration behavior. The velocity and spatial coordinates of the identified behavior are then predicted using the same neurological input data that was used for behavior identification. Results show that a nonlinear …
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The effects of exercise and omega-3 fatty acid supplementation as treatments for hepatic steatosis
… rats is their intrinsic aptitude for voluntary wheel running despite their obesity. OLETFs were randomly divided into 4 groups (n=8/group): 1) remained sedentary 2) access to running wheels (3) diet supplemented with 3% of energy from fish oil and 4) access to running wheels and diet …
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Therapeutic Aerobic Exercise in a Mouse Model of Breast Cancer: Effects on Tumor Progression, Angiogenesis, and Response to Chemotherapy
… mice. The exercise intervention (voluntary wheel running) was designed to mimic four clinically relevant scenarios: 1- patients who are sedentary before and after diagnosis, 2- previously sedentary patients who begin exercising after diagnosis, 3- previously active patients who stop …
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Regulation of Exercise-Dependent Cardiac Growth by MicroRNAs
… miR-499, is down-regulated by voluntary free-wheel running in hearts of mice. I hypothesized the reduction of miR-499 may be required for exercise-induced cardiac hypertrophy. I found forced cardiac over-expression of miR-499 was associated with diminished physiological cardiac growth, whereas …
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Linear mixed effects models in functional data analysis
… set to investigate the dependence of a mouse's wheel running distance on its body mass trajectory.
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Pituitary Adenylate Cyclase -Activating Peptide Signaling in the Mouse Circadian Clock
… clock resetting. Both behavioral measurement of wheel-running and electrophysiological measurements of spontaneous electrical firing rate rhythms show a selective alteration in late-night clock resetting in transgenic mice, compared with their PACAP-competent cousins. This alteration in the …
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