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Showing 1 to 2 of 2 for “"Wet stirred media milling"”.
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A preliminary investigation of the sterile-filterability of BCS class II drug nanosuspensions prepared via wet stirred media milling
… is to prepare naproxen (NPX) nanosuspensions via wet stirred media milling using various polymers and surfactants as stabilizers and to assess their physical stability with the ultimate goal of achieving the sterile filterability of such produced suspensions. An intensified milling process was …
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Batch and continuous production of stable dense suspensions of drug nanoparticles in a wet stirred media mill
… size of drug crystals down to nanoscale via wet stirred media milling. An increase in total surface area per mass loading of the drug and specific surface area as well as reduced external mass transfer resistance allow a faster dissolution of the poorly-water soluble drug from nanocrystals. …