Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"Wall stress"”.
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Abdominal aortic aneurysms : identification by self-examination and analysis of variation in matrix metalloproteinases with peak wall stress
… (FEA) of AAAs can define the area of peak wall stress area, the most likely site of rupture in engineering terms.Study 1Aim: To assess the effectiveness of self-examination for detection of AAAs compared to ultrasound measurement. The psychological consequences were also …
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Characterizing the role of central carbon metabolism and cell wall stress responses in Bacillus subtilis cell wall synthesis
The cell wall is an essential organelle for many bacteria since it provides mechanical strength and prevents bacterial cell lysis due to internal turgor pressure. Additionally, the cell wall is the first line of defense against various external stresses. The mesh of peptidoglycan is a major …
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Modelling of Residual Stresses of Blood Vessels
… with a suitably determined circumferential stress at arterial walls. The stress distribution over arterial walls in blood vessels is affected by residual stresses and stresses due to blood pressure. However, residual stresses are still not reliably determined. For this reason, a suitable …
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Advanced computer modeling of abdominal aortic aneurysms to predict risk of rupture
… aorta which is related to weakness of the vessel wall (associated with degradation of connective tissue), and if left untreated will lead to rupture and cause death in 78% to 94% of cases. Approximately 7,000 deaths each year in the United Kingdom are caused by AAA rupture.AAA repair requires …
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Endothelial Nitric Oxide Synthase and Growth Factor Regulation of Flow-Mediated Vascular Remodeling
… flow-mediated force in both vessels was shear stress with possible involvement of acute stretch-induced wall stress in the ileal artery. Significant luminal expansion and medial wall hypertrophy occurred in the ileal and second-order arteries in a time-dependent fashion. Increases in …
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The impact of diabetes on cardiac remodelling after myocardial infarction: potential role of thyroid hormone signalling
… cardiac function, growth and ischaemic stress. Acute myocardial infarction (AMI) was induced in age–match healthy control rats (AMI-C) and in streptozotocin (STZ)-induced type I diabetic (DM) animals (DM+AMI) using 35 mg/kg body weight while sham operated animals served as controls …
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A Filtered-Wall Formulation for Large -Eddy Simulation of Wall -Bounded Turbulence
… largely by difficulties in LES modeling near walls; this is commonly known as the LES 'wall-modeling' problem. To address the wall-modeling problem, a new approach for treating boundaries in the context of LES was developed. In this approach the wall is treated by 'filtering through it', so …
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MORPHOLOGY, MATERIAL AND VIBRATORY PROPERTIES OF THE SWIMBLADDER IN THE CARP, CYPRINUS CARPIO
… and auditory responses to mechanical strikes. Wall stress is higher in the posterior, strain in the anterior and modulus lower in the anterior chamber. Strikes increase pressure followed by a variable rebound that rapidly decays. Displacement and sound amplitude increase with hammer force, and …
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Predicting the risk of progression in patients with thoracic aortic aneurysm
… indexed AoD) +0.01(logTGFB1) -22.5(logIL2) c) wall stress estimations appear to provide even more robust predictions of future growth d) PBMC-RNA profiling could be useful as a diagnostic tool to detect patients with AD aneurysms.
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Effects Of Large-Scale Free Stream Turbulence On A Turbulent Boundary Layer
… deep into the boundary layer, affecting the wall stress as well as the small-scale (derivative) statistics. Energy spectra show a double peak. At very low free stream turbulence intensities these peaks are associated with the inner and outer scales of the turbulent boundary layer, but at high …
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Zweidimensionale Strain-Echokardiographie zur Analyse der regionalen linksventrikulären Funktion bei Aortenklappenvitien vor und nach operativem Aortenklappenersatz
… correlation between the reduction in meridonial wall stress after aortic valve replacement for AS and increase in radial strain. Conclusions: Myocardial deformation parameters change significantly soon after aortic valve replacement for aortic stenosis or aortic insufficiency indicating a …
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Oxidant-dependent regulation of L-type calcium channel activity by angiotensin in vascular smooth muscle
… regulation of blood flow. Increases in vessel wall stress or sympathetic activity stimulate vascular wall angiotensin signaling, resulting in smooth muscle contraction which directly increases peripheral resistance. Calcium influx through voltage-gated L-type calcium channels underlies vascular …
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A Stress-equivalent Spalart-Allmaras Wall Model with Local Boundary Conditions for RANS, DES, and LES
… to their effective use. In this thesis, a new wall model is developed based upon a modified version of the Spalart-Allmaras (SA) turbulence model that lessens the near-wall grid requirements. This is achieved by, below the log layer, making the eddy viscosity approach a constant, non-zero …
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Investigation of signalling involved in maintaining the mutually beneficial association between Epichloe festucae and perennial ryegrass : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Genetics at Massey University, Palmerston North, New Zealand
… search identified three candidate regulators: a stress activated MAP kinase, sakA, and the p21-activated kinases, pakA and pakB. To investigate if these genes were involved in symbiotic maintenance, replacement mutants were generated by homologous recombination. In culture analysis revealed that …
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Establishment and regulation of polar growth in Streptomyces
… lateral branching during normal growth and cell wall stress. I suggest that this is part of a stress response that provides Streptomyces with a mechanism to dismantle the apical growth apparatus at established hyphal tips that encounter problems with cell wall synthesis (for example through …
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Development of Novel Therapies for Marfan Syndrome using a Human iPSC-disease model
… removing the aneurysm or on minimising aortic wall stress by controlling haemodynamics, but neither of these strategies tackle the underlying pathology. Although MFS is caused by fibrillin-1 mutations, it remains unclear how these lead to the pleiotropic manifestations seen in patients. …
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Regulated intramembrane proteolysis in the control of the Bacillus subtilis anti-sigma factor RsiW.
… factor (RsiW). Initiated most likely by cell wall stress, RsiW is degraded by the mechanism of regulated intramembrane proteolysis (RIP). This process involves two site-specific proteolytic cleavage events in the extracytoplasmic part (site-1) and in the transmembrane domain (site-2) of RsiW. …
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Mechanisms of Early Brain Morphogenesis
… with changes in cytoskeletal contractility and wall stress. These results suggest a role for stress-based mechanical feedback in regulating epithelial development. We next investigated the more specific role of cytoskeletal contraction in forming the primary brain vesicles and rhombomeres that …
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Effect of ivabradine, a novel I<sub>f</sub> current inhibitor, on dynamic obstruction of the left ventricular outflow tract in cats with preclinical hypertrophic cardiomyopathy: a single-dose study
… in left ventricular systolic pressure, and thus wall stress, that may ultimately lead to progression of the disease. While prospective studies documenting the morbidity and mortality associated with dynamic obstruction have not been performed in feline HCM, it is possible that the results would …
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Cardiovascular Effects of Metformin on Left Ventricular Hypertrophy in Nondiabetic Patients with Coronary Artery Disease
… function, BP and biomarkers of cardiac wall stress and fibrosis, inflammation and oxidative stress.<br/><br/>In this study, we demonstrated 2000 mg daily of metformin therapy over a 12-month treatment period significantly reduced LVMI, LVM, office systolic blood pressure (SBP), body …
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