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Showing 1 to 2 of 2 for “"WH2-domain"”.
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Processive Acceleration of Actin Barbed End Assembly by N-WASP
… We used nanofibers coated with N-WASP WWCA domains as model cell surfaces and single actin filament imaging to determine how clustered N-WASP affects Arp2/3-independent barbed end assembly. Individual barbed ends captured by WWCA domains of N-WASP grew at or below their diffusion limited …
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Klonierung und funktionelle Analyse des Aktinreorganisators p150-Spir
… Hälfte eine Aufeinanderfolge von vier WH2-Domänen (Wiskott Aldrich Homology Domain 2) enthält. WH2-Domänen binden monomeres Aktin, Proteine mit WH2 Domänen, wie z.B. WASP oder WAVE sind Aktinreorganisatoren. Die transiente Überexpression von p150-Spir in NIH3T3-Mausfibroblasten führt …