Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"WDR35"”.
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Role of WDR35 in the formation of functional cilia
… role of one of the IFT-A complex protein WDR35/IFT121 in the formation of functional cilia by transporting structural elements of cilia via a vesicular mediated pathway. Null mutations in the IFT-A component WDR35/ IFT121 are embryonic lethal in both mouse models and human ciliopathies …
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Investigating the role of primary cilia loss in intrahepatic cholangiocarcinoma
… are deleted alongside the essential cilia gene Wdr35, I found that loss of cilia accelerated tumour development. In the absence of chronic inflammation, cilia loss in the context of tumour suppressor loss accelerated the development of biliary neoplasia. Bulk RNA sequencing of these tumour cells …