Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 31 for “"Vpr"”.
-
Visualizing Protease Activation, Retrochmp3 Activity, and VPR Recruitment During HIV-1 Assembly
… of recruitment of the HIV-1 accessory protein Vpr. I have also added significantly to science communication research through a study which evaluated the effectiveness of science summary methods. HIV-1 virions assemble at the plasma membrane of infected cells. The assembly of new viruses is …
-
Modulation of GR transcriptional signalling by HIV-1 Vpr insights into regulation by progestins
… (GC). One of the HIV-1 accessory proteins, Vpr, is highly immunosuppressive and contributes to suppression of the immune system thereby creating an environment favourable for viral proliferation. Vpr has been previously reported to act as a GR co-activator on glucocorticoid response element …
-
Polyploidy and Mitotic Cell Death are Two Distinct HIV-1 Vpr-Driven Outcomes in Renal Tubule Epithelial Cells
… in large part to viral proteins. Expression of Vpr in renal tubule epithelial cells (RTECs) induces G2 arrest, apoptosis and polyploidy. The ability of a subset of cells to overcome the G2/M block and progress to polyploidy is not well understood. Polyploidy frequently associates with a bypass …
-
Visual Place Recognition for Autonomous Robots
… input is termed as Visual Place Recognition (VPR) and refers to the ability of an autonomous system to recall a previously visited place using only visual input, under changing viewpoint, illumination and seasonal conditions, and given computational and storage constraints. This thesis is a …
-
The effects of HIV-1 viral protein r (vpr) and anti-retroviral drugs in the brain: Implications in HIV-1 associated neurocognitive disorders
… The importance of HIV-1 accessory protein Vpr has been well established in the pathology of AIDS in the peripheral and central nervous system. However, the role of Vpr in neuroinflammation and the underlying mechanisms involved have not been extensively studied. The RNA/Protein expression …
-
Visual Place Recognition under Severe Viewpoint and Appearance Changes
… and Mapping (SLAM). Visual Place Recognition (VPR), a core component of SLAM is a well-known paradigm. In layman terms, at a certain place/location within an environment, a robot needs to decide whether it’s the same place experienced before? Visual Place Recognition utilizing Convolutional …
-
Investigating the role of Trichodesmium spp. in the oceanic nitrogen cycle through observations and models
… primarily using the Video Plankton Recorder (VPR). A data processing procedure for estimating the abundance of rare taxa was devised to take advantage of the accuracy of manual classification and the effort savings of automatic classification. The procedure entails selecting a subset of the …
-
The viral protein R in HIV-associated acute ischaemic stroke: a case-control study
… Polymorphisms in HIV-1 viral protein R (Vpr) may alter its potential to promote endothelial dysfunction, by modifying its effects on viral replication, reactivation of latent cells, upregulation of proinflammatory cytokines and infection of macrophages. Methods: We analysed Vpr …
-
Role of the glucocorticoid receptor and HIV-1 Vpr in inflammatory gene expression and HIV-1 LTR transcription in response to dexamethasone and progestogens
… effects of the virion associated HIV-1 protein, Vpr, on GR-regulated inflammatory genes in the presence of the ligands.
-
Gene expression from unintegrated HIV-1 is restricted by the SMC5/6 complex
… upon delivery of the HIV-1 accessory protein Vpr, which degrades host target proteins via the host CRL4-DCAF1 cullin-RING ubiquitin ligase complex. To identify the responsible Vpr target, I performed a CRISPR-Cas9 forward genetic screen using a custom designed Vpr target sgRNA library. The …
-
Investigating the role of trichodesmium spp. in the oceanic nitrogen cycle through observations and models
… investigated through Video Plankton Recorder (VPR) and other observations collected in fall 2010 and spring 2011 in the western subtropical–tropical North Atlantic. A data processing procedure for estimating rare taxon abundance was devised to leverage the accuracy of manual classification and …
-
CAD for a 3-dimensional FPGA
… from the widely used Versatile Place and Route (VPR) CAD tool for 2-D FPGAs. The tool performs timing-driven placement of logic blocks in the 3-dimensional grid of the FPGA using a two-stage Simulated Annealing (SA) process. The SA algorithm in the original VPR tool has been modified to focus …
-
MONOCULAR VISUAL ODOMETRY
… in a monocular setup. Visual place recognition (VPR) can provide absolute pose estimates by matching the current camera frame to a database of reference images labeled with known coordinates. By using VPR to provide absolute pose estimates in the map and matching these estimates to the relative …
-
Regulation of cellular glucose metabolism by HIV-1 infection
… the proteomics core. HIV-1 encoded viral protein Vpr is essential for infection of macrophages by HIV-1. Vpr is known to cause cell cycle block in infected cell and bring about cell death. However, macrophages are resistant to cell death and are viral reservoir, even Vpr over expression does not …
-
Timing Driven Analytical Placement for FPGA
… undergoes low temperature Simulated Annealing in VPR to give comparable or better critical path delay and 8.7% bad overall wirelength after placement. Experimental results of 20 largest MCNC benchmark circuits show that our global placement engine outperforms the state-of-the-art academic placer …
-
Analyzing the role of a cellular mechanism in HIV infection and Evaluation of novel antiviral compounds
… yet in the case of HIV the viral protein R (Vpr), a small 14kDa accessory protein, is one candidate possibly implicated in the process. The protein stays associated to the PIC until nuclear translocation. Furthermore it has been shown, that Vpr binds to the nuclear pore complex (NPC). This …
-
Physical processes and zooplankton distribution in the Great South Channel : observational and numerical studies
… a new instrument, the Video Plankton Recorder (VPR); and a two-dimensional Eulerian numerical model that simulates one way in which a physical flow field, combined with a biological behavior pattern, may produce dense plankton patches at a convergent front. Part I: Data from a wide variety of …
-
Spatial Computing Frameworks for Adaptive Disaster Response and Visual Place Recognition
… on the Moon is Visual Place Recognition (VPR), which involves matching one or multiple image sets in order to determine which images show the same places in the world. As there is a severe lack of lunar imagery to train our models on, we have created a model, Despina, for synthesis of …
Page 1 of 2