Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 24 for “"Vitiligo"”.
-
Histopathologic Features in Vitiligo
… It is sometimes difficult to differentiate vitiligo from other hypopigmented disorders only by clinical features. However, only a few reports are available on histopathological changes in vitiligo. PURPOSE: The purpose of the study was to delineate the microscopic alterations that are …
-
Automatic 3D surface area measurement for vitiligo lesions
Vitiligo is a long term skin depigmentation disease that may result in psychological stress. Monitoring changes in vitiligo lesion area allows assessment of treatment efficacy and aids in clinical decision making. Currently existing approaches for vitiligo lesion measurement are either inefficient …
-
Only skin deep: examining vitiligo from a biopsychosocial perspective
… stems from empirical work carried out with vitiligo sufferers over a period of 3 years, from 1995 to 1998. Vitiligo is a pigmentation disorder, which causes the destruction of melanocytes in the skin. The affected areas lose their pigmentation resulting in the appearance of irregular white …
-
Melanocyte survival and response to treatment in Vitiligo Patients
Vitiligo is a common depigmenting skin disorder with devastating psychological implications. Although evidence strongly suggests that melanocytes die in various forms of vitiligo, it is also evident, at least in certain cases, that melanocytes/melanoblasts survive in an undifferentiated stem cell …
-
An exploration of men's subjective experience of Vitiligo : a qualitative study
Vitiligo is a chronic skin disorder, which de-pigments parts or all of the skin. This disfiguring condition presents individual sufferers with many challenges. Studies have shown an adverse psychological impact of living with such a skin condition. However, no studies to date have explored the …
-
Is melanoma associated leucoderma (MAL) a distinct entity compared to classial vitiligo?
Patients with classical vitiligo lose partially their protecting inherited pigment. The cause of the disease is still unknown. Despite massive epidermal oxidative / nitrative stress and signs for DNA-damage in the skin and in the plasma, these patients have no higher prevalence for sun induced …
-
The Psychosocial Impact of a Social Interaction Skills Training (SIST) Workshop for Vitiligo Patients
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
-
Defining a Role for Inducible Heat Shock Protein 70 (HSP70i) In Mediating Autoimmune Vitiligo
<p>Vitiligo is an autoimmune disease characterized by destruction of melanocytes, leaving 0.5% of the population with progressive depigmentation. Current treatments offer limited efficacy. Observations that heat shock proteins (HSPs) can serve as adjuvants in antitumor vaccines first suggested to …
-
More evidence for H2O2-mediated oxidative stress in vitiligo-increased epidermal DNA damage / repair.
… as well as in the system in patients with vitiligo (for review see (Schallreuter, Bahadoran et al. 2008). Xanthine dehydrogenase / xanthine oxidase (XDH / XO) catalyses the oxidative hydroxylation of hypoxanthine to xanthine followed by xanthine to uric acid, the last two steps in purine …
-
H2O2-mediated oxidation and nitration enhances DNA binding capacity / DNA repair via up-regulated epidermal wild-type p53 in vitiligo.
The entire epidermis of patients with vitiligo exhibits accumulation of up to 10-3M concentrations of hydrogen peroxide (H2O2) (Schallreuter, Moore et al. 1999). Over the last decade our group and others have focused on the effect of H2O2-mediated oxidative stress on the function of many proteins …
-
Comparison of coping, quality of life and psychosocial well-being in children and adult patients with vitiligo before and after treatment with pseudocatalase PC-KUS. A questionnaire-based investigation into social anxiety, helplessness, anxious-depressive mood, quality of life and depression before and after treatment with pseudocatalase PC-KUS depending on demographic characteristics and experiences.
Vitiligo is an idiopathic, non-contagious and often familial depigmentation disorder affecting both sexes equally. The mostly progressive and patchy loss of the inherited skin colour is not only a cosmetical problem, it has a profound impact on the patient¿s well-being. Stigmatisation and rejection …
-
FOXP3, ICOS and ICOSL polymorphisms in an Italian population affected by systemic sclerosis
… disease, ulcerative colitis, multiple sclerosis, vitiligo, type-1 diabetes, rheumatoid arthritis, and ankylosing spondylitis. Although analysis tests did not show any significant associations between the SNPs under study and SSc, the occurrence of FOXP3 rs2294020 in female patients was associated …
-
An in vitro investigation of the effect of Khellin and UVA (KUVA) on normal and transformed human melanocytes
… UVA) and other treatments currently in use for vitiligo, have justified the search for an alternative treatment. In this study, the use of khellin, a naturally occurring furochromone, which is similar in structure to psoralens, is explored as an alternative treatment for vitiligo. When khellin …
-
Hypomelanosis in chickens
… certain human hypomelanotic disorders, such as vitiligo and albinism. To determine whether melanocytes are present in the hypomelanotic skin, two melanocyte-specific assays were carried out, in situ DOPA histochemistry and a sensitive radiometric assay for tyrosinase. The results show that …
-
Expression and Function of Toll-Like Receptor 2 and 4 in Human Melanocytes
… synthesis. TLR2 expression was decreased in vitiligo lesion compared with normal skin. These findings suggested that TLR2 and TLR4 may play a role in the microbial-induced melanogenesis.
-
Health-Related Quality of Life in Morphea
… diseases, including non-melanoma skin cancer, vitiligo, and alopecia (lowest P <.0001). The morphea population was found to have significantly worse global HRQOL scores than the general U.S. population for all subscales (all P ≤.004) with the exception of bodily pain. Comorbidity (r =.35-.51, P …
-
Dermatological Concerns For Women and Girls With Turner Syndrome
… Some conditions like dry skin, lymphedema, vitiligo, abnormal nails, and history of skin biopsy due to a suspicion for skin cancer were especially predictive of deleterious impact on quality of life. Our data reveal that many skin conditions are highly prevalent in the TS population during …
-
Clinical and Histopathological Characteristics of Nevus Depigmentosus
… melanin and melanocytes may also be present in vitiligo skin. Therefore, both clinical and histologic findings should be considered together to make a diagnosis of ND.
Page 1 of 2