Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Vitamin D -- Metabolism"”.
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Applications of Disposable Pipette Extraction for Analysis of Drugs of Abuse Vitamin D Metabolism Testosterone and Inborn Errors of Metabolism by Gas and Liquid Chromatography/mass Spectrometry
… extraction) resin. The method analyzed all major vitamin D metabolites including the frequently-ignored but important and tough structural isomer of 25-hydroxyvitamin D3. DPX extraction efficiency was high with over 90% recovery. Intra-day and inter-day precisions are less than 5% even at the …
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Déploiement et évaluation d’une offre de test de dépistage néonatal pour le rachitisme vitamino-dépendant de type 1A
Vitamin D-Dependent Rickets Type 1A (VDDR1A) is an autosomal recessive inherited disease caused by variants in the CYP27B1 gene, which is required for vitamin D activation. Although rare worldwide, the prevalence is 1 in 2916 births in the Saguenay-Lac-Saint-Jean (SLSJ), Haute-Côte-Nord (HCN) and …
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Vitamin D status and requirements during pregnancy and lactation
Vitamin D deficiency during pregnancy, lactation, and early infancy has been widely reported. Current understanding of vitamin D metabolism during pregnancy and lactation is incomplete, and to date, experimental data to support vitamin D requirements for these life stages are scarce. There is a …
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1,000 ancient genomes uncover 10,000 years of natural selection in Europe
… in previous scans, with many associated with vitamin D metabolism. Strikingly, 17 out of 19 of the candidates from the Neolithic and Bronze Age periods were not previously detected, highlighting the unique power of ancient DNA to reveal selective events not uncoverable in modern samples due to …
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Role of Vitamin D receptor and vitamin D binding protein restriction fragment length polymorphisms in determining dose response to vitamin D: a randomized double blind placebo controlled trial
Serum 25-hydroxyvitamin D (25OHD) is considered to be the best biomarker of vitamin D status. Besides the dietary intake of vitamin D and exposure to sunlight, there are other factors that affect serum 25OHD such as weight, race, sex, binding protein and the effect of vitamin D receptor (VDR) and …
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Developmental Malformations in Zebrafish Caused by Exposure to Environmental Pollutants
… RT-qPCR to predict that these compounds affect vitamin D metabolism and dopamine transporters resulting skeletal malformations. Transcriptomics data identified that exposure to cyproconazole, a prominent SDC, induce adipogenesis, while repressing osteo and chondrogenesis. Next, we investigated …
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Early life phenotypes of type 1 diabetes genetic risk
… to affect growth mediated by hormones, vitamin D, or the microbiome. Genotypes were determined in ~600 children and used to derive high-risk T1D HLA haplotypes and genetic risk scores. Examination of data in the CBGS defined the contributors to physiological growth and set the framework …
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Osteoporosis in rheumatoid arthritis
… the relationships with sex hormonal status or vitamin D metabolism. Future research should aim at cohort analysis at 2 different periods, in order to improve our understanding of the pathogenesis of bone loss in RA.
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The Impact of Vitamin D Status upon Markers of Athlete Health
… At present there is a pandemic of low serum vitamin D (25[OH]D) concentration, partly due to a lack of sun exposure (the primary route for synthesis) and modern lifestyle choices. The bioactive form of vitamin D, 1,25-dihydroxyvitamin D (1,25[OH]2D3) exerts its biological activity by binding …