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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 96 for “"Vitamin B12"”.
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Protein binding of vitamin B12
Thesis (M.S.)--Michigan State University. Dept. of Food Science, 1967
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Vitamin B12 Bioconjugates In Pharmaceutical Design
… addresses several questions focused on the vitamin B12 (B12) dietary uptake pathway, in particular that of the enteric B12 transport protein intrinsic factor (IF) and its receptor cubilin, and the expression and exploitation of IF/cubilin in pharmaceutical development.</p> <p>Q1: (Chapter 2) …
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Studies on the Function of Vitamin B12
Made available in DSpace on 2014-12-05T17:47:37Z (GMT). No. of bitstreams: 1 5904582.pdf: 2964999 bytes, checksum: 91380d1d0dd3934e93174fb4ca2d2775 (MD5) Previous issue date: 1959
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Studies on the Function of Vitamin B12
Made available in DSpace on 2014-12-05T17:47:49Z (GMT). No. of bitstreams: 1 6200692.pdf: 3372016 bytes, checksum: e8122653146345ab8f85a6527157b8f3 (MD5) Previous issue date: 1961
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Investigations on the Metabolic Role of Vitamin B12
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1960.
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Studies in Protein Biosynthesis. Role of Vitamin B12 and Rna
Made available in DSpace on 2014-12-05T17:47:39Z (GMT). No. of bitstreams: 1 6000216.pdf: 2459688 bytes, checksum: 5115bd08aed59ee78d9b931e150cffdb (MD5) Previous issue date: 1959
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Insights into vitamin B12 production, acquisition, and use by marine microbes
… essential aspects of marine biogeochemistry. Vitamin B12, also known as cobalamin, is a cobalt containing organometallic micronutrient produced by some bacteria and archaea and required by many eukaryotic phytoplankton for methionine biosynthesis and regeneration. Although the potential for …
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Bio-enrichment of vitamin B12 in plant-based food via fermentation
Vitamin B12 deficiency is common among individuals following strictly plant-based diets. This issue is amplified by the growing preference for organic products, which are often not vitamin-fortified. As vitamin B12 is naturally produced by bacteria, fermentation offers a sustainable strategy to …
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Physical and Biological Studies With Free and Protein Bound Vitamin B12
Made available in DSpace on 2014-12-09T17:36:48Z (GMT). No. of bitstreams: 1 7020994.pdf: 4592797 bytes, checksum: bf8034f96e537736f00914f0e09bf43a (MD5) Previous issue date: 1970
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The Effect of Vitamin B12 on Some Aspects of Glycine Metabolism
Made available in DSpace on 2014-12-05T17:47:30Z (GMT). No. of bitstreams: 1 0018121.pdf: 2167910 bytes, checksum: e93268df47773e06beaff180af494b56 (MD5) Previous issue date: 1956
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Investigating the molecular basis of vitamin B12 uptake in Chlamydomonas reinhardtii
… an external supply of the corrinoid cobalamin (vitamin B12) for growth. Algal phyla differ in the proportion of species dependent on B12. Extremes of this are the Chlorophyta (30% B12 dependent) and the Dinophyta (91% B12 dependent). B12 is only synthesised by prokaryotic organisms, therefore, …
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Vitamin B12 impacts amyloid-β induced proteotoxicity by regulating the methionine/s-adenosylmethionine cycle
… effect of HB101 was due to the availability of vitamin B12. Vitamin B12 supplementation delayed Aβ-induced paralysis and protected against energy defects in animals raised on OP50, a B12 deficient E. coli, but had no additive effects for Aβ animals fed HB101. Interestingly, a decrease in B12 …
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The relationship between rotifers, vitamin B12, and selected environmental parameters in Pandapas Pond, Virginia
Vitamin B12 concentrations, measured as combined, uncombined, and total, were determined in Pandapas Pond, Virginia, June through December 1977. Average summer vitamin B12 concentrations (all forms) were higher than during the fall and winter. Mean concentrations of combined, uncombined, and total …
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Toward a Cell-Based Assay for Cubam-Mediated Intrinsic Factor-Vitamin B12 Binding and Uptake
Background: Vitamin B12 deficiency caused by intrinsic factor (IF) autoantibodies can lead to pernicious anemia. The 2025 iGEM project aimed to develop a novel oral B12 supplement capable of escaping autoantibody recognition. This study was designed to complete and continue the iGEM project with …
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Vitamin B12-mediated physiology, mutualisms, and gene regulation studies in Chlamydomonas reinhardtii and Phaeodactylum tricornutum
… symbiosis with bacteria where the latter provide vitamins such as cobalamin (vitamin B12) in exchange for fixed carbon from the algae. Vitamin B12 is used as a cofactor by methionine synthase (METH), but many algae such as the freshwater chlorophyte, Chlamydomonas reinhardtii, and the marine …
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The associations between plasma homocysteine, vitamin B12, folate, the Apolipoprotein E genotype and Alzheimer's Disease
… presence of the Apolipoprotein ε4 allele, low vitamin B₁₂ and folate levels, and elevated plasma homocysteine concentrations. Most research involving the associations between these risk factors and AD have been conducted in Europe and North America. We know little about AD and its risk factors …
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A METE mutant of Chlamydomonas reinhardtii provides new perspectives on the evolution of vitamin B12 auxotrophy
Vitamin B12 is synthesised only by prokaryotes yet is widely required by eukaryotes as an enzyme cofactor. Roughly half of all algae require vitamin B12, and the phylogenetic distribution of this trait suggests that it has evolved on multiple occasions. Previous work using artificial evolution …
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Studies on the metabolism of Hymenolepis diminuta with special reference to desoxyribonucleic acid, vitamin B12 and fat
The studies reported herein are part of an overall program devoted to the task of providing sufficient factual information for a more complete understanding of the physiology of the rat tapeworm, Hymenolepis diminuta, and the relationships that it has with its host. There are essentially two lines …
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Investigating the genomic, transcriptomic and metabolic landscape of Chlamydomonas reinhardtii in the context of vitamin B12 availability
… of algal biology including their predominately vitamin B12 dependency is however desperately needed. While de novo biosynthesis of nature’s most complex vitamin is limited to prokaryotes, a vast number of eukaryotic species, comprising all mammals and more than half of all algal species, require …
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Riboswitch regulation of methionine metabolism and vitamin B12 uptake in mycobacteria – implications for drug susceptibility and pathogenesis
Alterations in the genetic capacity for cobamide biosynthesis have been identified as potentially critical in the evolution of Mycobacterium tuberculosis from a putative environmental ancestor. Moreover, recent studies have implicated cobamide biosynthesis pathway genes in the adaptation of the …
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