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Showing 1 to 20 of 22 for “"Vitamin B1"”.
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Genetic Engineering of Plant Seeds to Increase Thiamin (Vitamin B1) Content
Thiamine (Vitamin B1) in the form of thiamine pyrophosphate (TPP) is an essential cofactor for the function of numerous enzymes which are involved in central metabolism such as citric acid cycle, pentose phosphate pathway, Calvin cycle, isoprenoid biosynthesis, and branched-chain amino acid …
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Structural insights into conformationally-gated reactions catalyzed by thiamine pyrophosphate-dependent enzymes
… into DXP, an essential precursor of isoprenoids, vitamin B1, and vitamin B6 (pyridoxal phosphate, PLP) in bacterial pathogens. Human adapts different pathways to access those essential metabolites; thus, selective inhibition of DXP synthase has been considered to be a possible approach for …
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Design and Synthesis of Thiamine Pyrophosphate (TPP) Analogues for Investigating the Structure-Activity Relationship (SAR) of Inhibitors of TPP-dependent Enzymes
… pyrophosphate (TPP), the bioactive form of vitamin B1, is an essential coenzyme needed for processes of cellular metabolism in all organisms. TPP-dependent enzymes all require the coenzyme TPP for catalytic activity, although individual members vary significantly in substrate preferences and …
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Interaction between dietary thiamine and lipid in juvenile steelhead trout
Thiamine (vitamin B1) deficiency has been negatively affecting salmonines in the Great Lakes region. This project investigated the hypothesis that thiamine deficiency in steelhead trout is a result of a high lipid diet due to thiamine being used up as an antioxidant to prevent lipid peroxidation. …
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Indigenous knowledge on utilization aspects and nutritional profiling of selected edible wild fruits from Zambia.
… 1.60 ± 0.417 to 13 ± 1.41 mg/kg DW respectively. Vitamin A ranged from 52.5 ± 4.94 to 187.5 ± 13.4 mg/kg DW, vitamin B1 ranged from 68.58 ± 5.21 to 142.06 ± 36.50 mg/kg DW, vitamin B2 ranged from 0.001 ± 0.00 to 0.18 ± 0.28 mg/kg DW, vitamin B9 ranged from 1.235 ± 0.106 to 2.385 ± 0.106 mg/kg DW …
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Studies of thiamine biosynthesis
… coli, and other prokaryotes, thiamine (vitamin B1) is assembled by coupling 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate (Hmp-PP) and 4-methyl-5-(?-hydroxyethyl)thiazole phosphate (Thz-P). The thiazole moiety is biosynthesised from 1-deoxyxylulose-5-phosphate, tyrosine, and …
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Neue Heterazoliumsalze aus Prolin und Pyroglutaminsäure und Anwendungen in Carben-katalysierten asymmetrischen nucleophilen Acylierungen
The coenzyme thiamine (vitamin B1), a natural thiazolium salt, is involved in many enzymatic catalyses in vivo. It has been proposed that the catalytically active species of these reactions is a nucleophilic carbene. Consequently, enzyme mimetic asymmetric catalytic processes that are mediated by …
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Peningkatan viabilitas (Priming) benih juwawut(Setaria italica (L.) P. Beauvois) dengan menggunakan Polyethylene Glycol (PEG) 6000
… sebagai sumber energi, protein, kalsium, vitamin B1, riboflavin (vitamin B2). Produksi juwawut (Setaria italica (L.) P. Beauvois) dalam negeri cenderung menurun disebabkan oleh banyak faktor, satu diantara faktor yang diduga menjadi penyebab adalah viabilitas benih. Oleh karena itu perlu …
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The design and synthesis of a novel thiamine cofactor for potential biocatalysis
… has concentrated on the synthesis of unnatural vitamin B1 motifs containing a central 1,4 - triazole motif (figure 1) first synthesised by Leeper in 2006. Figure 1: 1,4 – disubstituted triazole ThDP Synthesis of a cofactor that could theoretically carry out alternative reaction pathways and …
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Microbial Genome Evolution Due to Multifaceted Symbiosis within the Tsetse Fly (Diptera: Glossinidae)
… of nutrient provisioning, specifically thiamine (Vitamin B1), for the maintenance of a stable symbiotic environment within the tsetse host. These studies demonstrated that Sodalis required exogenous thiamine for proliferation due to the erosion of biosynthetic capabilities, while Wigglesworthia …
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Analisis kondisi dan potensi lama fermentasi medium kombucha (teh, kopi, rosela) dalam menghambat pertumbuhan bakteri patogen (Vibrio cholerae dan Bacillus cereus)
INDONESIA: Minuman fermentasi kombucha mengandung Vitamin B1, B2, B3, B6, B12, B15, C, asam folat, asam glukoronat, asam glukonat, asam asetat, asam khondrotin sulfat, asam hyaluronik, asam laktat, acetaminophen, asam amino esensial dan enzim. Senyawa yang terkandung didalam minuman kombucha dapat …
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Exploring Prokaryotic Thiamin Biosynthesis: Mechanistic Studies On Thiamin Thiazole Synthase And Pyrimidine Synthase
Thiamin (Vitamin B1) is made from a coupling a thiazole and a pyrimidine unit, which are assembled separately. Studies have shown that the biosyntheses of thiazole and pyrimidine are different in prokaryotes versus eukaryotes. Understanding of thiamin biosynthesis is still incomplete and a lot of …
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The Role of Nutrient Availability in Therapeutic Response of Leukemia
… pyrophosphate kinase 1 (TPK1), which converts vitamin B1 (thiamine) into the cofactor thiamine pyrophosphate (TPP), as a metabolic dependency under ASNase treatment. In glutamine-anaplerotic leukemia cells, we found that TPP availability enables asparagine synthesis from extracellular …
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Identification and characterization of thiamine biosynthesis, transport, and regulation elements among bacteroides species
Thiamine (vitamin B1) is an essential cofactor for all organisms. Humans primarily acquire thiamine through their diet and thiamine deficiencies have adverse neurological effects. However, the role gut microbes play in modulating thiamine availability is poorly understood. In addition, little is …
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The crystal and molecular structure of thiamine hydroiodide /|nWilliam Edward Lee. -- 260 St. Catharines [Ont.] : Dept. of Chemistry, Brock University,
The x-ray crystal structure of thiamine hydroiodide,C1ZH18N40S12' has been determined. The unit cell parameters are a = 13.84 ± 0.03, o b = 7.44 ± 0.01, c = 20.24 ± 0.02 A, 8 = 120.52 ± 0.07°, space group P2/c, z = 4. A total of 1445 reflections having ,2 > 2o(F2), 26 < 40° were collected on a …
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Palladium and platinum complexes of vitamin Bâ
… (PN)2' cis-PdCI2 (PN)2 and cis-PdC12 (PL)2 the vitamin B6 ligands are coordinated to the metal through the pyridine ring nitrogen. The compounds [PLH+ ]2[PtCI6] 2- .H20 and [PMH2] 2+ [PdCI4] 2- .H20have no direct metal-ligand bonding, In all the complexes, the metal maintains a square planar …
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Determination of thiamine in solution by UV-visible spectrophotometry: The effect of interactions with gold nanoparticles
<p>The method presented here provides the foundation for a simple and selective qualitative determination of thiamine in solution. Gold nanoparticles in the presence of thiamine results in the formation of a secondary peak in the absorbance spectrum of the mixture. This peak can be used as an …
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