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Showing 1 to 3 of 3 for “"Viscosupplementation"”.
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A comparison of the functional efficacy of osteoarthritic knee joints following viscosupplementation treatment
The purpose of this study was to compare two viscosupplementation products, Hyalgan and Synvisc, that may be used to treat osteoarthritis (OA) of the knee. Hyalgan and Synvisc, have both been studied extensively against NSAIDS and placebos and have both yielded significantly greater improvements in …
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The Mechanism of Action of Hyaluronan Therapy as a Treatment for Osteoarthritis and the Assessment of Osteoarthritic Articular Cartilage Using Ultrasound
… explanation of the treatment known as <i>viscosupplementation</i>, which assumes that HA acts primarily by increasing the viscosity of synovial fluid. Given that the biological half-life of HA in synovial fluid is approximately two days—far shorter than the duration of clinical benefit—the …
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Design of Biomaterials toward Endogenous Skeletal Tissue Repair
… replenishing native hyaluronic acid with viscosupplementation is commonly used in clinics, its therapeutic efficacy is largely inconsistent at least in part due to the short joint retention. To enhance the longevity and chondroprotective function of hyaluronic acid supplementation, I …