Global ETD Search

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Showing 1 to 3 of 3 for “"Visceral nociception"”.

  1. Regulation of Visceral Nociception by GPR35

    … mechanical modalities, such as the distention of visceral organs or by mediators released in response to gut inflammation. Pain management in these conditions is challenging due to the side effects associated with commonly used analgesics, and so a significant unmet clinical need exists for the …

    cambridge Repository record for Regulation of Visceral Nociception by GPR35 (opens in a new tab)

  2. Sex as a Biological Variable in Preclinical Animal Studies with an Infectious Disease Exemplar.

    … integrity, epithelial barrier function, visceral nociception, microbiome recovery and reproductive endpoints, HtrA was well tolerated in both male and female mice. Importantly, reproductive assessments, including ovarian follicle development and testicular histology, demonstrated no …

    queens Repository record for Sex as a Biological Variable in Preclinical Animal Studies with an Infectious Disease Exemplar. (opens in a new tab)

  3. Targeting pro-inflammatory mediators to treat visceral pain

    Visceral pain is a prominent cause of morbidity in gastrointestinal (GI) diseases, like inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), but many current analgesics produce GI side effects. To develop much needed, novel treatments, further understanding of the pro-inflammatory …

    cambridge Repository record for Targeting pro-inflammatory mediators to treat visceral pain (opens in a new tab)