Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Virulence attenuation"”.
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Analyzing the Role of Mucin O-Glycans in Regulating Microbial Virulence
… glycans that are sufficient for mucins’ virulence attenuation. Lastly, I investigate the expression and production of virulence factors in the enteric pathogen, V. cholerae and demonstrate that mucin O-glycans, specifically Core 2- derived glycans, inhibit the major determinants of …
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Molecular dissection of competence regulated virulence in Streptococcus pneumoniae
… system directly contributes to pneumococcal virulence during pneumonia and bacteremia, independent of DNA uptake. Competence is activated when the competence stimulating peptide (CSP), encoded by the comC gene, is processed and exported through the ComAB transporter and stimulates the …
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FUNCTIONAL CHARACTERIZATION OF PAPAIN-LIKE PROTEASE p48 REQUIRED FOR REPLICATION OF HYPOVIRUS CHV-1 RESPONSIBLE FOR VIRULENCE-ATTENTUATION OF THE CHESTNUT BLIGHT FUNGUS
… hypovirus CHV-1/EP713, responsible for virulence attenuation (hypovirulence) of the chestnut blight fungus <italic>Cryphonectria parasitica</italic>, encodes two leader papain-like proteases, p29 and p48, at the N-terminus of ORF A and ORF B, respectively. Protease p29 has been shown to …
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Characterization of virulence-attenuated Listeria monocytogenes common among food and food-associated environments but rarely associated with disease
Studies were conducted to characterize virulence-attenuated Listeria monocytogenes isolates carrying single nucleotide polymorphisms (SNPs) leading to a premature stop codon (PMSC) in the key virulence gene, inlA. The virulence factor Internalin A (InlA; encoded by inlA), facilitates the uptake of …