Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Virulence (Microbiology)"”.
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Impaired virulence factor production in a dihydroorotate dehydrogenase mutant (pyrD) of Pseudomonas aeruginosa.
… for pyrimidines but they were also impaired in virulence factor production. Such a correlation had not been previously reported for P. aeruginosa, a ubiquitous opportunistic pathogen in humans. In an earlier study it was reported that mutants blocked in one of the first three enzymes of the …
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A genetic screen to identify novel Helicobacter pylori virulence factors using Saccharomyces cerevisiae as a model eukaryotic cell
… of this study was to identify novel H pylori virulence factors, to further elucidate their role in H pylori virulence and their potential as novel effectors of the cag PAI. In the work presented here, we generated an H pylori genomic plasmid library and screened this library in Saccharomyces …
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Pathogenesis of experimental tuberculosis in guinea pigs
… granuloma necrosis. Our studies showed that the virulence of clinical isolates of M. tuberculosis was reflected in more severe and widely disseminated disease in experimentally infected guinea pigs and was a better predictor of virulence than the bacterial burden determined by culture. These data …
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Serotype Association and Regulation of the Hyaluronate Lyase Gene of <i>Streptococcus pyogenes</i>
<p><em>S. pyogenes</em> expresses many virulence factors, controlled by a complex regulatory network. These include hyaluronate lyase, an enzyme that degrades hyaluronic acid, a major component of the human extracellular matrix. Paradoxically, hyaluronic acid is also the sole component of the …