Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Virulence (Microbiology)"”.
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Transcriptional Adaptation of Enterococcus faecalis within Macrophages and the Role of PerA in Virulence
The intestinal ecosystem is comprised of bacteria that are both beneficial and detrimental to human health. The opportunistic pathogens residing within the gastrointestinal tract typically function as commensal members of the human microbiota. However, in certain circumstances these bacteria are …
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Impaired virulence factor production in a dihydroorotate dehydrogenase mutant (pyrD) of Pseudomonas aeruginosa.
… for pyrimidines but they were also impaired in virulence factor production. Such a correlation had not been previously reported for P. aeruginosa, a ubiquitous opportunistic pathogen in humans. In an earlier study it was reported that mutants blocked in one of the first three enzymes of the …
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A genetic screen to identify novel Helicobacter pylori virulence factors using Saccharomyces cerevisiae as a model eukaryotic cell
… of this study was to identify novel H pylori virulence factors, to further elucidate their role in H pylori virulence and their potential as novel effectors of the cag PAI. In the work presented here, we generated an H pylori genomic plasmid library and screened this library in Saccharomyces …
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Pathogenesis of experimental tuberculosis in guinea pigs
… granuloma necrosis. Our studies showed that the virulence of clinical isolates of M. tuberculosis was reflected in more severe and widely disseminated disease in experimentally infected guinea pigs and was a better predictor of virulence than the bacterial burden determined by culture. These data …
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Serotype Association and Regulation of the Hyaluronate Lyase Gene of <i>Streptococcus pyogenes</i>
<p><em>S. pyogenes</em> expresses many virulence factors, controlled by a complex regulatory network. These include hyaluronate lyase, an enzyme that degrades hyaluronic acid, a major component of the human extracellular matrix. Paradoxically, hyaluronic acid is also the sole component of the …