Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Virtual drug screening"”.
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A Pharmacological Strategy Against African Sleeping Sickness
… leading to death. Currently there are 5 approved drugs used to treat it, each with toxic side effects and effective at specific disease stages. A more effective and less toxic drug candidate is highly sought after. The essential enzyme, dUTPase, is an excellent drug target in the parasite while …
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Foundations of Machine Learning: Over-parameterization and Feature Learning
… completion problems such as image inpainting and virtual drug screening. Additionally, we use the NTK connection to provide theoretical guarantees for deep neural networks. Namely, we construct interpolating infinitely wide and deep networks that are Bayes optimal, or consistent, for …
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Structure based design of a ricin antidote
… and is an attractive target for structure-based drug design. Aided by computer docking simulations, several ricin toxin A chain (RTA) inhibitors have been identified; the most promising leads belonging to the pterin family. To date, the most potent RTA inhibitors developed using this approach are …