Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Viral sensing"”.
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Evolutionary analysis of Suidae TLR signaling pathway
… To this end, coding sequences of bacterial sensing TLR (TLR1, TLR2 and TLR6) and viral sensing TLR (TLR3, TLR7 and TLR8) were retrieved from resequencing libraries of one animal representing each of the following members of the family Suidae: Sus scrofa from Europe, Sus scrofa from Asia, …
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The Role of HOIL 1 Ubiquitin Ligase Activity in MDA5 Antiviral Signaling
… RIG-I and MDA5 both signal to MAVS to induce antiviral cytokine induction but respond to different viruses and are activated by distinct mechanisms. The mechanisms regulating RIG-I signaling has been extensively characterized, while considerably less Is known about MDA5 activation and signal …
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Molecular Mechanism of MDA5 RNA Sensing in Innate Immunity and Disease Pathogenesis
… a crucial role in recognising and combating viral infections. Double-stranded RNA (dsRNA) is a potent proinflammatory signal, and its recognition by MDA5 and its coregulatory factor, LGP2, is essential for initiating antiviral responses. This study aimed to investigate the structure and …