Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"Viral load suppression"”.
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How accurately do routinely reported HIV viral load suppression proportions reflect progress towards the 90-90-90 target in the population on ART in Khayelitsha, South Africa?
… In 2016, Khayelitsha reported almost 89% viral load (VL) suppression but less than 56% completion on routine quarterly reports, casting doubt on the validity of reported suppression. Objectives: To assess the validity of reported VL suppression as a measure of progress towards the 90-90-90 …
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Paediatric antiretroviral HIV treatment : measurement and correlates of adherence in a resource-poor setting
… amongst four, which best correlates with viral load suppression; as well as correlates of adherence amongst a cohort of children younger than 7 years on antiretroviral HIV treatment. Design: A Prospective cohort study with 6 months follow-up [ Methods ] Measures of adherence used: …
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Therapeutic and virological outcomes in adults living with HIV / AID at 6 and 12 months after initiation of first-line highly active antiretroviral therapy in an urban population in Namibia
Antiretroviral regimens have side effects that can threaten adherence by patients resulting in evolution of viral resistance due to suboptimal drug levels. Studies have shown that drug adherence of at least 80% can result in viral load suppression. There is no literature on the association between …
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A formative and outcome evaluation of a community based antiretroviral therapy adherence programme : the case of Sizophila, Cape Town, South Africa
… Sizophila programme, a community based antiretroviral therapy (ART) programme. The programme is administered by the Desmond Tutu HIV Foundation, a non-profit organization. The aim of the programme is to enhance ART health outcomes and promote individual wellbeing among people accessing human …
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Antiretroviral Regimen and Pregnancy Outcomes of Women Living with HIV in a US Cohort
… Immediate initiation of antiretroviral therapy (ART) is recommended for women who are pregnant and living with HIV. Given there is limited data regarding the safety of ART in pregnancy, high-quality research of maternal and fetal outcomes in women who are pregnant and on ART is of …
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Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies
… the same setting. Outcomes included maternal Viral Load (VL), HIV testing at 9 and 18 months of age, and other maternal and child health outcomes. Results During the implementation of PNC study period, n=484 MIP were recruited with 84% overall attendance, 95% overall viral load suppression, …
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A copula approach to sample selection modeling of treatment adherence and viral suppression among HIV patients on antiretroviral therapy (ART) in Namibia
… the 90-90-90 strategy on testing, treatment and suppression has not been evaluated. Moreover, examining factors associated with treatment adherence and viral suppression will assist in designing appropriate accelerated interventions. However, modelling treatment adherence and viral suppression …
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Evaluation of HIV test and treat strategy in Windhoek, Namibia: Development of an operational framework
… evidence that supports the use of Antiretroviral Therapy (ART) treatment for the prevention of HIV. The study aims to develop an operational framework based on the assessment and identification of pitfalls in the current HIV Test and Treat strategy implemented in Namibia, specifically …
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Perceived factors associated with LTFU from Art Program among adults living with HIV in Vhembe District, South Africa
… threat to the long-term success of the Anti-Retroviral therapy program. The success of Anti-Retroviral therapy program is monitored through retention in care and viral load suppression. This study describes perceived factors associated with loss to follow-up. A quantitative approach, cross …
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Prevalence, predictors and HIV disease progression in immunovirogical discordant HIV patients at 12 months of first line antiretroviral therapy in Zambia.
Combined antiretroviral therapy (cART) has improved mortality and morbidity among HIV-infected patients. However, a third of HIV-infected patients still present to care with advanced disease despite the rollout of cART. Some of these patients fail to appropriately reconstitute their immune system …
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Comparison of resting state functional networks in HIV infected and uninfected children at age 9 years
… children who are on highly-active antiretroviral therapy (ART), with viral load suppression from a young age. Here, we use resting state fMRI (rs-fMRI) to examine the impact of HIV and ART on the development of functional networks in 9-year-old vertically HIV-infected children compared to …
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Factors associated with delay in starting anti-retroviral treatment among confirmed HIV positive individuals in state health facilities in Northern Namibia
… associated with the delay in starting anti-retroviral treatment (ART) among confirmed HIV-positive individuals in Northern Namibia, specifically the four (4) districts of the UTAP region (Andara, Nyangana, Oshikuku and Tsumeb). The study employed the time series analytical (quantitative) research …
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Outcomes of children transferring out of Red Cross War Memorial Children's Hospital HIV cohort using linkage to the National Health Laboratory Service Data
Background and Rationale: Paediatric antiretroviral (ART) care in the Western Cape Province (WCP) has evolved following South Africa's (SA) massive roll-out of antiretroviral therapy in 2004 in response to the country's human immunodeficiency virus (HIV) epidemic. Decentralization of paediatric ART …
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Universal antiretroviral therapy (ART) for infants and young children living with HIV: assessing the effect of guideline changes on ART initiation characteristics and treatment outcomes in resource-limited settings
… HIV treatment towards universal antiretroviral therapy (ART) allowing for immediate initiation of ART, regardless of clinical or immunologic status initially for infants, and subsequently for progressively older, and ultimately all children. Given the scale-up of early infant diagnosis …
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Moving from pediatric to adolescent HIV care in Northern Tanzania: exploring transition services, perceptions and self-care during early adolescence
… due to increased coverage and access to antiretroviral therapy (ART) for children in Sub Saharan Africa (SSA), the pediatric-to-adolescent transition in HIV care is now of public health importance. There is, however, limited information available regarding pediatric-to-adolescent transition …
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The effect of long-term azithromycin treatment on the respiratory microbiota of HIV-infected children with chronic lung disease
… (6-12 and 13-19 years), and duration of antiretroviral therapy use (6 months to < 2 years and ≥ 2 years). All samples were cultured for Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae and Moraxella catarrhalis and other Gram-negative bacilli. Antibiotic susceptibility …
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An assessment of external HIV-related stigma in South Africa: implications for interventions
… the progression from HIV testing to durable viral load suppression among people living with HIV. The targets guide HIV programmes to achieve 90% known HIV status, to access 90% antiretroviral therapy and to suppress 90% viral loads (UNAIDS, 2017). Achievement of the 90-90-90 targets has since …
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Functional Genome-wide Association Studies (fGWAS) and genomics landscape of signatures of polygenic adaptation in Botswana populations with HIV-1 C infection
… early introduction of second generation antiretrovirals like dolutegravir (DTG), the first African nation to reach the 2030 UNIAIDS targets (95-95-95), and a 0.3% decrease in mother-to-child transmission rates. However, the main limitations include the spread of HIV 1C that is resistant to …