Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Viral antagonism"”.
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The Evolution of the Viral RNA Sensor OAS1 in Old World Monkeys and Cetartiodactyls
… environment poised to detect and respond to viral infection. The oligoadenylate synthetase family of enzymes comprises a crucial part of this innate immune response, directly signaling endonuclease activity responsible for inhibiting viral replication. Oligoadenylate synthetase 1 plays a …
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Functional Characterisation of Protein Degradation during Human Cytomegalovirus Infection
… proteins for degradation. Insights into this viral antagonism can facilitate the development of novel antiviral therapies by restoring the activity of endogenous proteins important for antiviral restriction and immunity. A previous multiplexed proteomic approach identified 35 ‘high-confidence’ …
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Gene expression from unintegrated HIV-1 is restricted by the SMC5/6 complex
Integration of viral DNA into the host genome is the hallmark of human immunodeficiency virus 1 (HIV-1) infections. However, in early infection, the most abundant viral DNA species are extrachromosomal unintegrated viral genomes, which despite being competent for gene expression, are poorly …