Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Viral Transmission"”.
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Inferring Determinants of Viral Transmission using Short-Read Sequence Data
… genetic framework generating insights into viral transmission events based upon genome sequence data collected before and after transmission. Previous attempts at bottleneck estimation have neglected the underlying genetic structure of viruses, considering instead less informative …
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The Effect of the Incorporation of Heavy Metal Zeolites into 3-D Printed Surgical Guide Resin on the Surface Stability of SARS-CoV-2
… spread around the world at an alarming rate. The transmission was of great concern, as was the ability of the virus to survive in the environment for extended periods of time. Zeolites and heavy metals have unique properties that can reduce the risk of infection by inhibiting the transmission of …
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Factors That Influence Murine Norovirus Stability and Tropism
… bacteria and bacterial components could impact viral thermostability. I found that that specific Gram-positive bacteria and conditioned medium from Gram-positive bacteria could stabilize MNV against heat inactivation. However, I found that Gram-negative bacteria and conditioned medium had no …
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Natural Product Discovery from a Streamline Environment-to-Bioassay Pipeline
… bacterium S. ureilytica M01 as a source of antiviral NPs. Bioassay guided fractionation and spectroscopic analyses led to the isolation and characterization of glucosamine derivatives with activity against Chikungunya virus. Ongoing work aims to elucidate their mechanism of action and the role …
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COVID-19 Vaccine Hesitancy in a US Public University Cohort
… mixing patterns that may increase risk of viral transmission within and between social groups. Understanding attitudes toward vaccine uptake is critical to strategic reopening. At the University of Washington, we conducted a prospective observational study of SARS-CoV-2 surveillance in …
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Ecological and evolutionary aspects of interactions between microbes coinfecting plants
… Coinfection timing significantly influenced viral within-host competition. Additionally, simultaneous coinfections were significantly more severe than sequential coinfections, which were only as severe as the most damaging constituent virus. A mathematical model was used to demonstrate that …
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The epidemiology of Lagos bat virus and henipaviruses in straw-coloured fruit bats (Eidolon helvum), using population genetics to infer population connectivity
… Ghana aim to better understand E. helvum and viral ecology, as well as the nature of human-bat interactions. To assess whether the findings from these studies can be extrapolated across the species’ continental range, more information on the movement ecology of the species and connectivity of …
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La Crosse virus and Dirofilaria immitis: Abundance of Potential Vectors in Southwestern Virginia and the Effects of Dual Infection on Aedes albopictus and Ochlerotatus triseriatus
Microfilarial enhancement of viral transmission is well documented, however only one previously studied model used components that occur together in nature and therefore has realistic implications. La Crosse (LAC) virus encephalitis is the most common mosquito-borne illness affecting children in …
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Within Host and Multiscale Models of Usutu and SARS-CoV-2 Viral Infections with Animal Hosts
… to uncover mechanistic interactions governing viral infections. To acquire a holistic understanding of the impact of viral infections, it is necessary to develop mathematical techniques and models that bridge knowledge on multiple biological scales. This dissertation explores the relationship …
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Factors That Influence Mammalian Enteric Virus Infection
… to mutations generated by the error-prone viral RNA-dependent RNA polymerase during replication. Despite the ability to acquire mutations beneficial to the virus, most mutations are deleterious and reduce viral fitness. This poses an obstacle for RNA viruses to successfully infect the host. …
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Vectors of Health: Epidemics, Ecologies, and the Reinvention of Mosquito Science in Brazil
… called Wolbachia, a microbe that can inhibit viral transmission. In Recife, a group sterilized male mosquitoes through irradiation, releasing these insects to mate with wild ones on the island of Fernando de Noronha and prevent future A. aegypti generations. The third group, in Foz do Iguaçu, …
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Detection and description of influenza a virus transmission in commercial weaned pigs in Illinois, USA
… hosts for infectious pathogen amplification and transmission. Very few point-of-care tests are available for livestock, with only one commercially licensed product for influenza detection in swine. We developed a pandemic Matrix gene detection method via Reverse Transcription Loop-Mediated …
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Counteracting Neuroinvasive RNA Viruses: Antiviral and Immune Modulation Strategies Against SARS-CoV-2 and VEEV
… played a critical role in decreasing viral spread among communities. In instances where social distancing practices were implemented (minimum 6 feet), people quarantine upon feeling ill or exposure to positive cases, proper mask usage by both the infected and uninfected individual, and …