Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Viral Immunology"”.
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Using the single-cycle flavivirus particle replivax to study flavivirus replication and immune response
… of genome leads to the production of subviral particles (SVP) and NS1 antigens that are highly immunogenic and induce an antiviral immune response without causing disease. The overall goal of this dissertation was to understand the interaction of RepliVAX with target cells, innate immune …
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Role of Multiple Toll-Like Receptor Activation in Regulating Cytotoxic T Cell Priming to Lympocytic Choriomeningitis Virus Infections
… activation and affect their abilities to clear viral infection. However, how TLR ligands (TLR-L) can regulate CD8+ T cell responses have not been fully elucidated. This thesis will focus on examining how the presence of components from foreign pathogens, e.g. viral or bacterial infection, can …
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Exploring antiviral effector cells in vaccinia virus-infected tissues
… cells in tissues. To understand antiviral immunity in critical barrier tissues, this study investigated the spatial organisation of both leukocytes and VACV-infected cells in two different models: epicutaneous infection of the skin and a newly developed model of mouse lip (labial …
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Identification of Viral Determinants of Murine Norovirus Pathogenesis
… importance as human pathogens, knowledge of the viral life cycle and host pathogenesis is limited due to the lack of practical models to study. In contrast, murine norovirus: MNV) has been a critical surrogate for the study of human noroviruses as it is the only member of this genus that …
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Viral Factors Influencing Early Infection Events During Ex-Vivo KSHV Infection
… for addressing fundamental questions about basic immunology and virology knowledge regarding this virus. Kaposi Sarcoma Herpes Virus (KSHV), also known as Human Herpesvirus 8 (HHV8), is the etiological agent of Kaposi Sarcoma (KS) and other lymphoproliferative cancers, such as Multicentric …