Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Violacein"”.
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Structural studies of rebeccamycin, staurosporine, and violacein biosynthetic enzymes
… products rebeccamycin, staurosporine, and violacein from the common starting material L-tryptophan involves shared enzymatic transformations. However, the pathways diverge at two steps, each involving a reactive, bisindole intermediate. We have taken a structural approach to characterize …
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Combining microbial functional metagenomics and Caenorhabditis elegans genetics to uncover and characterise novel bioactive compounds
… including the small molecules tambjamine and violacein, which appear to facilitate bacterial colonisation and induce apoptosis in the nematode. An array of genes and gene products involved in antinematode activities was also identified including a gene encoding for a novel protein involved in …
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Designing a Gateway Cloning Lab Showcasing the Pigment from Chromobacterium violaceum for Molecular Biology Lab Classes
… bacterium Chromobacterium violaceum, cloning the violacein operon using polymerase chain reaction, and placing the cloned operon into E. coli using Gateway cloning methods. The final product produces E. coli cells that express the entire five gene violacein pathway, and as a result produce the …
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Comparative genomics of bacteria from amphibian skin associated with inhibition of an amphibian fungal pathogen Batrachochytrium dendrobatidis
… activity against fungi, including chitinase and violacein. We identified a difference in the number, as well as amino acid sequences, of predicted chitinases found in two isolates belonging to the genus Agrobacterium that varied in their inhibition of Bd. After examining the annotated genomes, we …
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Metagenomics-Based Tryptophan Dimer Natural Product Discovery and Development Pipeline
… such as staurosporine, rebeccamycin, and violacein. To discover novel tryptophan dimers (TDs), we have designed a metagenomics-based TD natural product discovery and development pipeline that consists of seven steps: 1) soil eDNA extraction; 2) eDNA library construction; 3) homology-based …