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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"Vif"”.
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The Dynamic Interplay Between Lentiviral Vif and Human APOBEC3 Proteins
… HIV-1 counteracts restriction with its Vif protein, which nucleates a ubiquitin ligase complex that directly binds A3 enzymes and targets them for proteasomal degradation. My thesis research aims at understanding the dynamic interplay between lentiviral Vif and human A3 enzymes, from the …
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Nt-VIF - ein proteinogener Inhibitor der Vakuolären Invertasen in Tabak
… sowie insbesondere der vakuoläre Inhibitor Nt VIF der Modellpflanze Nicotiana tabacum (Tabak) wurden im Rahmen dieser Arbeit molekularbiolo¬gisch und bio¬chemisch näher charakterisiert. Die partiellen Sequenzen von VIs aus Tabak (Nt VI) und Kartoffel (St VI) wurden ver¬vollständigt. Bei etwa …
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Structural studies of HIV-1 Vif and its SOCS-box domain
… cells. The viral infectivity factor (Vif) can induce a poly-ubiquitination degradation of APOBEC3G to counteract the immune response by forming an E3 ubiquitin complex composed of cellular proteins Elongin B (EloB), Elongin C (EloC), Cullin 5 and Ring-Box protein. In this project, we …
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Lethal Hypermutation Induced by the Innate Cellular Restriction Factor APOBEC Destroys HIV-1 in Infected Humanized Mice
… however, they are neutralized by the HIV-1 Vif protein. In vitro, the absence of Vif allows the enzymatic activity of APOBEC3G and 3F to induce hypermutation of the HIV-1 genome. These observations make the Vif/APOBEC axis a tantalizing therapeutic target. The ability of APOBEC to restrict …
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Measurement of The Vascular Input Function In Mice For Dce-Mri
… upon measurement of the vascular input function (VIF), which represents the contrast agent concentration time course in the blood plasma. This is difficult in small animal models due to artifacts associated with partial volume, inflow enhancement, and the limited temporal resolution achievable …
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Managing Weeds and Soilborne Pests with Fumigant and Non-Fumigant Alternatives to Methyl Bromide
… pathogens of tomato. Virtually impermeable film (VIF) and totally impermeable film (TIF) were tested for fumigant retention and yellow nutsedge control in tomato. Grafting onto resistant rootstocks was tested for bacterial wilt and nematode management in tomato. In the absence of a soil fumigant, …
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Ektopische Expression von Nt-CIF und Nt-VIF in Kartoffelpflanzen : Posttranslationale Inhibition der wundinduzierten ZWI- und VI-Aktivitäten zur Aufklärung ihrer in vivo-Funktionen
… of ß-Fructosidase/ ZWI-Inhibitor) und Nt-VIF (Nicotiana tabacum Vacuolar Inhibitor of ß-Fructosidase/ VI-Inhibitor) eingesetzt. Die Expression der Inhibitorproteine bedingt die posttranslationale Inhibition der ZWI-Aktivität in den Nt-CIF-Transformanten, bzw. der VI-Aktivität in den …
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APOBEC3 Transcriptional Regulation and HIV-1 Restriction in T Lymphocytes
… cytosine deaminases. In the absence of the viral Vif protein, multiple APOBEC3 enzymes can package into virions budding from an infected cell. Following virus entry into a new target cell, the APOBEC3 enzymes catalyze the deamination of cytosines to uracils in viral reverse transcription …
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Diversity in APOBEC3 and CCR5 host genes and HIV-1 in a South African population
… HIV, and the HIV viral infectivity factor (Vif) protein serves to antagonize the action of APOBEC3 proteins, promoting viral replication. The CCR5 co-receptor and the HIV Env V3 loop have also been documented as playing roles in HIV-1 disease progression. The interplay between host and viral …
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Finanças comportamentais: análise dos fatores do efeito manada em empresas listadas na [B]3- Brasil Bolsa Balcão
… In addition, the Variance Inflation Factor (VIF) and the tolerance value (1/VIF) were tested for multicollinearity; The Wooldridge autocorrelation; And those of White and Breusch Pagan heteroscedasticity. In general, the results found indicated a positive relationship between the herd …
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Restriction of Retrotransposition and Retroviral Infection by RNase L and APOBEC3G
… between RNase L and APOBEC3G during HIV-1 delta Vif infection was investigated in Chapter 3. I found both A3G and RNase L were packaged into HIV-1 delta Vif virions. Virions containing A3G in the absence of RNase L exhibited higher infectivity compared to virons containing both proteins, which …
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Sustainable approaches to control Calonectria diseases in ornamental nursery
… ridotte e utilizzando due film plastici (TIF e VIF) per la pacciamatura del suolo fumigato. I dati ottenuti hanno consentito di accertare che metham-sodio e dazomet applicati a dosi ulteriormente ridotte (fino a 5 volte inferiori) sono risultati efficaci nel ridurre la vitalità dei …
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Prevalencia y factores asociados al síndrome visual informático en estudiantes de un colegio de Neiva-2025.
… el cálculo del factor de inflación de varianza (VIF, por sus siglas en ingles). Se consideraron indicativos de colinealidad problemática los valores de VIF superiores a 5. Resultados: la prevalencia del SVI fue del 58,9%. Las manifestaciones más frecuentes fueron: dolor de cabeza (68,3%), prurito …
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The role of political and institutional factors in Central Asian trade integration : evidence from the gravity model
… test, along with a correlation matrix and VIF, were performed to evaluate the trustworthiness of the dataset alongside its validity. The findings include higher trade values due to increased GDP from the exporting country, as well as inflow of foreign direct investment, which are positive …
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Robust Statistical Modeling In Functional Linear Regression
… using a robust group variable inflation factor (VIF) selection procedure. Our methodology is validated through rigorous simulation studies as well as its application to real-world data. To ensure the cohesiveness of this dissertation, Chapter 1 provides an introduction to the research background, …
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Molecular Mechanisms and Host Factors Involved in HIV-1 Latency
… promoter, 2) into non-replicative pNL4 ∆env ∆vif viral expression vector, and 3) into a replicative pNL4-CXCR4 viral vector to study infection and induction by latency reversal agent (LRA) treatment to better understand the mechanism of latency and transcriptional induction. Viruses produced …
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Digital Watermarking Based Image and Video Quality Evaluation
… accuracy in terms of PSNR, wPSNR, JND, SSIM and VIF under JPEG compression, JPEG2000 compression, Gaussian low-pass filtering, Gaussian noise distortion, H.264 compression and packet loss related distortion.
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INTERACTIONS BETWEEN THE GLYCOSYLATED GAG PROTEIN OF A MURINE LEUKEMIA VIRUS AND MURINE APOBEC3: NOVEL INSIGHTS INTO HOW A MURINE LEUKEMIA VIRUS COUNTERACTS A RESTRICTION FACTOR
… action of the APOBEC proteins. HIV encodes the Vif protein which binds to hA3G and facilitates its rapid degradation through the proteasome. The mechanism(s) by which exogenous MuLVs evade mA3 inhibitory activity is unknown.</p> <p>Exogenous MuLVs encode a glycosylated gag protein (gGag) …
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INTERACTIONS BETWEEN THE GLYCOSYLATED GAG PROTEIN OF A MURINE LEUKEMIA VIRUS AND MURINE APOBEC3: NOVEL INSIGHTS INTO HOW A MURINE LEUKEMIA VIRUS COUNTERACTS A RESTRICTION FACTOR
… action of the APOBEC proteins. HIV encodes the Vif protein which binds to hA3G and facilitates its rapid degradation through the proteasome. The mechanism(s) by which exogenous MuLVs evade mA3 inhibitory activity is unknown.</p> <p>Exogenous MuLVs encode a glycosylated gag protein (gGag) …
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