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Showing 1 to 3 of 3 for “"Viable cell density"”.
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Biocapacitance Sensors for In-Line Viable Cell Density Monitoring in Complex Bioreactors
The precise monitoring of Viable Cell Density (VCD) in bioreactors is crucial for optimizing bioprocesses, improving yield, and maintaining product quality. VCD can be effectively indicated by biocapacitance, a capacitance associated with the viable cell membrane, which can be detected through …
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Development of dielectric spectroscopic monitoring methods for the prediction of viable cell density and volume in mammalian cell culture
… methods for the real-time prediction of viable cell density and viable cell volume in Chinese hamster ovary cell cultures. This work focuses on the use of Biomass Monitor for the monitoring of biomass. Two dual frequency settings and 2 temperatures were examined. The effects of …
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Industry 4.0 in Biomanufacturing: Predictive Real-Time Models Using Process Analytical Technology
… this thesis, we collect capacitance and optical density data from two in-line sensors in production bioreactors to compute real-time readings of viable cell density (VCD) and viability, two critical metrics that drive product quality and batch yield. Comparing predictions with manually collected …