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Showing 1 to 8 of 8 for “"Vessel mimic"”.
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Implementation of Physiologic Pressure Conditions in a Blood Vessel Mimic Bioreactor System
… of Physiologic Pressure Conditions in a Blood Vessel Mimic Bioreactor System Kevin Mark Okarski Tissue engineering has traditionally been pursued as a therapeutic science intended for restoring or replacing diseased or damaged biologic tissues or organs. Cal Poly’s Blood Vessel Mimic Laboratory …
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Tissue Engineering a Blood Vessel Mimic While Monitoring Contamination Through Sterility Assurance Testing
<p><em>Tissue Engineering A Blood Vessel Mimic While Monitoring Contamination Through Sterility Assurance Testing</em></p> <p>Navid Djassemi</p> <p>Tissue engineering blood vessel mimics has been proposed as a method to analyze the endothelial cell response to intravascular devices that are used in …
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Development of an In-Vitro Tissue Engineered Blood Vessel Mimic Using Human Large Vessel Cell Sources
… and therapies. Specifically, in-vitro blood vessel mimics (BVM) have been developed to create a bench-top blood vessel model using human cells that can be used to test and evaluate vascular disease treatments and intravascular devices. Previous BVM work has used fat derived human …
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Characterization and Implementation of a Decellularized Porcine Vessel as a Biologic Scaffold for a Blood Vessel Mimic
… recently developed a tissue engineered blood vessel mimic, with the goal of testing intravascular devices. However, the scaffold component of this model exhibits several physiological limitations that must be addressed to create a truly biomemtic BVM. The current model uses expanded …
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Identifying and Reducing Variability, Improving Scaffold Morphology, and Investigating Alternative Materials for the Blood Vessel Mimic Lab Electrospinning Process
… characterization, and improvement of “Blood Vessel Mimics” (BVMs), tissue engineered constructs used to evaluate cellular response to vascular medical devices. Currently, cells are grown onto fibrous, porous tubes made using an in-house electrospinning process from PLGA, a biocompatible …
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Development and Characterization of Tissue Engineered Blood Vessel Mimics Under "Diabetic" Conditions
<p>The development of tissue engineered blood vessel mimics for the testing of intravascular devices in vitro has been established in the Cal Poly tissue engineering lab. Due to the prevalence of cardiovascular disease in diabetic patients and minimal accessible studies regarding the interactions …
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Evaluation of Endothelial Cell Responses to Elevated Glucose
<p>Developing a tissue-engineered Blood Vessel Mimic (BVM) to represent diabetic macrovascular disease could expedite design of new vascular devices specifically tailored to diabetic patients. In contribution toward this model, this thesis assessed Human Umbilical Vein Endothelial Cell (HUVEC) …
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Fluid Dynamic Assessments of Spiral Flow Induced by Vascular Grafts
… haemodynamics produced by a graft in the host vessel is believed to significantly affect endothelial function. Single spiral flow is a normal feature in medium and large sized vessels and it is induced by the anatomical structure and physiological function of the cardiovascular system. Grafts …